Silicocarnotite Synthesis and Bioactivity in Artificial Saliva Medium

Abstract

The aim of this study is the synthesis and investigation of bioactive response of acrystalline silicophosphate.A monophasic silicocarnotite was elaborated by solid state reaction from a mixture of beta-tricaliciumphosphate and dicalcium silicate based on mussel shells according to the diagram of system Ca3(PO4)2–Ca2SiO4, at 65 % and 35% respectively , these starting materials are heated up to 1450 °C to obtain a monophasic silicocaronitite. The obtained result probed that the main crystalline phase which was detected and recognized in the heated sample at 1400 and 1450 °C was a well-crystallized silicocarnotite. The test of bioactivity of silicocarnotite in artificial saliva causes the appearance of a reaction layer on the materials surface after 4 hours soaking and growth up during 30 days.This layer is constituted of a biphasic mixture of Si–Ca–P–H material, silicated hydroxyapatite and hydroxyapatite phase are the mainly developing ones with increasing soaking time.The analysis and characterization of the precipitated appearing on the material surface has confirmed experimentally the in vitro bioactivity of silicocarnotite monophasic material.

High-temperature phase transformations of hydroxylapatite and the formation of silicocarnotite in the hydroxylapatite–quartz–lime system studied in situ and in operando by Raman spectroscopy

“…Recently, highly promising studies with silicon-substituted calcium phosphates have shown that silicon is an essential trace element for bone mineralization and can improve the bioactivity of calcium phosphate materials [36][37][38][39][40][41]. The wide range of CaO, SiO 2 , and P 2 O 5 solid solutions varies with temperature and makes silicocarnotite (Ca 5 (PO 4 ) 2 SiO 4 ) [32,34,[42][43][44][45] an excellent ceramic with great potential for medical applications [41,[45][46][47][48], which creates interest in knowledge about its synthesis conditions [35,46,49,50].…”