1995
DOI: 10.1159/000188360
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Significance of Urinary Fibrin/Fibrinogen Degradation Products in Renal Diseases Measured by a Highly Sensitive ELISA

Abstract: The urinary fibrin/fibrinogen degradation products (FDP), as sensitive indicators of various renal disorders, have been measured by several methods. For their determination, a new and highly sensitive enzyme-linked immunosorbent assay not requiring the urine concentration has been developed. The study comprised 42 patients with nonnephrotic chronic glomerulonephritis (CGN), 23 patients with primary nephrotic syndrome (NS), and 29 healthy adults. The results were as follow: (1) the content of urinary FDP in nor… Show more

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Cited by 5 publications
(3 citation statements)
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“…I; black bars) of these 76 athletes. This is consistent with previous ly reported data obtained at rest in haemodialysed pa tients and control subjects not submitted to rHuEpo treat ments [6] and with recent data reported by Shibata et al [12] in healthy adults.…”
Section: Discussionsupporting
confidence: 93%
“…I; black bars) of these 76 athletes. This is consistent with previous ly reported data obtained at rest in haemodialysed pa tients and control subjects not submitted to rHuEpo treat ments [6] and with recent data reported by Shibata et al [12] in healthy adults.…”
Section: Discussionsupporting
confidence: 93%
“…However, in the present study, we did not find estrogen use to be associated with D‐dimer levels (analyses not shown). Higher D‐dimer levels were independently associated with lower eGFR in both men and women, probably as a result of decreased clearance by the kidney [26,27]. Renal insufficiency is associated with increased levels of inflammatory and procoagulant biomarkers, including CRP, interleukin‐6 (IL‐6), fibrinogen, and D‐dimer [28].…”
Section: Discussionmentioning
confidence: 99%
“…We previously reported the results of measurement of urinary FDP in renal dis eases using a newly established sensitive en zyme-linked immunosorbent assay (ELISA) [3]. Up to now there arc few' reports on abnormalities of fibrinolysis, especially sc rum FDP, in renal diseases.…”
Section: Significance Of Serum Fibrin/fibrinogen Degradation Productsmentioning
confidence: 99%