Significance of Plasmodium berghei Amino Acid Transporter 1 in Food Vacuole Functionality and Its Association with Cerebral Pathogenesis

Anand, Aditya; Chandana, Manjunatha; Ghosh, Sourav; Das, Rahul; Singh, Nalini; Vaishalli, Pradeep Mini; Gantasala, Nagavara Prasad; Padmanaban, Govindarajan; Nagaraj, Viswanathan Arun

doi:10.1128/spectrum.04943-22

Microbiol Spectr

2023

DOI: 10.1128/spectrum.04943-22

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Significance of Plasmodium berghei Amino Acid Transporter 1 in Food Vacuole Functionality and Its Association with Cerebral Pathogenesis

Aditya Anand

Manjunatha Chandana

Sourav Ghosh

et al.

Abstract: Food vacuoles of the malaria parasite are involved in the degradation of red blood cell hemoglobin. The amino acids derived from hemoglobin degradation support parasite growth, and the heme released is detoxified into hemozoin.

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Phytochemical screening, antioxidant analyses, and in vitro and in vivo antimalarial activities of herbal medicinal plant - Rotheca serrata (L.) Steane & Mabb.

Chanu,

Chatterjee,

Singh

et al. 2024

Journal of Ethnopharmacology

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Phytochemical screening, antioxidant analyses, and in vitro and in vivo antimalarial activities of herbal medicinal plant - Rotheca serrata (L.) Steane & Mabb.

Chanu,

Chatterjee,

Singh

et al. 2024

Journal of Ethnopharmacology

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Significance of Plasmodium berghei Amino Acid Transporter 1 in Food Vacuole Functionality and Its Association with Cerebral Pathogenesis

Abstract: Food vacuoles of the malaria parasite are involved in the degradation of red blood cell hemoglobin. The amino acids derived from hemoglobin degradation support parasite growth, and the heme released is detoxified into hemozoin.

Cited by 1 publication

References 70 publications

Phytochemical screening, antioxidant analyses, and in vitro and in vivo antimalarial activities of herbal medicinal plant - Rotheca serrata (L.) Steane & Mabb.

Phytochemical screening, antioxidant analyses, and in vitro and in vivo antimalarial activities of herbal medicinal plant - Rotheca serrata (L.) Steane & Mabb.

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