Significance of bizarre cells in cervical screening liquid‐based cytology: A prospective study of 15 cases

Abstract

Objective: The aim of this study was to assess the significance of bizarre cells (cells of squamous origin with a superficial squamous cell-type cytoplasm and characterised by multinucleation that produces bizarre nuclear shapes) in liquid-based cytology (LBC) Papanicoaou (pap) smears with clinical and histological follow-up correlation.Methods: Fifteen patients, all with LBC samples containing bizarre cells, were identified in routine ThinPrep â LBC workload. HPV testing was performed in each case using residual LBC material. Cytological-histological correlations were reviewed. In this study, we have taken a step further to prospectively identify LBC pap smear cases containing bizarre cells as described earlier