Signal amplification of dopamine using lanthanum hexacyanoferrate-modified electrode

Abstract

A sensitive and selective electrochemical sensor has been developed using an electroactive polynuclear lanthanum hexacyanoferrate (LaHCF) complex with counter alkali cation (Na +) deposited on the glassy carbon (GC) electrode (GC/LaHCF). The GC/LaHCF-modified electrode is found to be an excellent transducer in mediating the oxidation of neurotransmitter molecule such as dopamine (DA) at physiological pH 7.2. Interestingly, the GC/LaHCF-modified electrode amplifies a 50-fold enhancement in the oxidation of DA signal compared to the bare GC electrode. Besides, the GC/LaHCF-modified electrode shows excellent selectivity in the voltammetric oxidation of DA in the presence of ascorbic acid (AA). Under optimal conditions, the GC/LaHCF modified electrode shows a linear relationship in DA oxidation between 0.1 × 10 −6 and 1.0 × 10 −6 M with the detection limit of 1 × 10 −8 M (10 nM). Importantly, practical utility of the modified electrode is good in studying the real sample analysis such as dopamine hydrochloride injection assay.

Ruthenium Oxide Hexacyanoferrate as an Effective Electrode Modifier for Amperometric Detection of Iodate and Hydrogen Peroxide

“…The MHCF electrocatalytic effects were confirmed for H 2 O 2 , 1,4,10 NO 11 and some easily oxidizable species as ascorbic acid, 2,8 dopamine, 2,6 glucose, 9 sulfite. 5,7 The preparation of hexacyanoferrate films with ruthenium also has been reported.…”

“…Various metals have been used to prepare MH-CF-modified electrodes by chemical 4 or electrochemical 2,[5][6][7][8][9][10][11] methods. Data show that most of the modified electrodes were prepared via electrochemical deposition techniques owing to its low cost, low time consuming and well-defined structure forming ability by controlling the time, cycle number and nature of the electrolyte.…”

$$\mathrm{NiFe}_{2}\mathrm{O}_{4 }$$ NiFe 2 O 4 nanoparticles-decorated activated carbon nanocomposite based electrochemical sensor for selective detection of dopamine in presence of uric acid and ascorbic acid

“…Tremendous efforts were carried out using various nanomaterials such as polymers, 7-9 metal nanoparticles, 10-15 core@shell nanostructures, 16,17 alloys, 18,19 two-dimensional layered materials, [20][21][22] carbon based [23][24][25][26] and metal/metal oxide nanocomposites. [27][28][29][30][31][32][33][34][35][36] Yin et al, reported a three-dimensional MoS 2 nanosheet for simultaneous detection of DA, UA and AA. 37 The peak separation for AA-DA, DA-UA and AA-UA were found to be 208.3 mV, 128.0 mV and 336.3 mV, respectively.…”

Controlled electrochemical synthesis of new rare earth metal lutetium hexacyanoferrate on reduced graphene oxide and its application as a salicylic acid sensor

“…In spite of the overwhelming activity on metal hexacyanoferrate, rare earth metal-HCFs have also been widely used in electrochemical sensor applications. [16][17][18][19][20] To date, several rare earth metal-HCFs such as dysprosium, 21,22 samarium, 23,24 and lanthanum HCF, 25 respectively, have been reported for preparation and characterization. Nonetheless, rare earth metal-HCFs have fascinating morphologies such as ower and christmas tree-like CeHCF, 26 diamond-like NdHCF, 27 LaHCF, 28 and parabola-like HoHCF.…”