Sicherheit und Effektivität eines in Electron-Beam-Melting-Technik hergestellten Titan-Mesh-Cages zur intersomatischen lumbalen Fusion

Zippelius, Timo; Strube, Patrick; Suleymanov, Farid; Putzier, Michael; Hölzl, Alexander

doi:10.1007/s00132-018-03681-7

Cited by 5 publications

(1 citation statement)

References 14 publications

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“…Bionic structures can also be considered. Zippelius et al designed a “banana-shaped” cage made of Ti with curved rails on the surface that can help embed the endplates of the vertebrae, securing the cage to the desired location on the ventral edge strip (such as on the rails) while extending the surface and facilitating better skeletal integration, and they obtained a good fusion rate in 60 patients by using this approach ( Zippelius et al, 2018 ). In addition, Kim et al designed a scalable interbody device (inserted in the form of contraction and expanded in situ after being correctly located in the intervertebral space), which is suitable for minimally invasive interbody fusion.…”

Section: Strategies For Designing Interbody Fusion Cagesmentioning

confidence: 99%

Biomaterials for Interbody Fusion in Bone Tissue Engineering

Zhang

Wang

et al. 2022

Front. Bioeng. Biotechnol.

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In recent years, interbody fusion cages have played an important role in interbody fusion surgery for treating diseases like disc protrusion and spondylolisthesis. However, traditional cages cannot achieve satisfactory results due to their unreasonable design, poor material biocompatibility, and induced osteogenesis ability, limiting their application. There are currently 3 ways to improve the fusion effect, as follows. First, the interbody fusion cage is designed to facilitate bone ingrowth through the preliminary design. Second, choose interbody fusion cages made of different materials to meet the variable needs of interbody fusion. Finally, complete post-processing steps, such as coating the designed cage, to achieve a suitable osseointegration microstructure, and add other bioactive materials to achieve the most suitable biological microenvironment of bone tissue and improve the fusion effect. The focus of this review is on the design methods of interbody fusion cages, a comparison of the advantages and disadvantages of various materials, the influence of post-processing techniques and additional materials on interbody fusion, and the prospects for the future development of interbody fusion cages.

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Section: Strategies For Designing Interbody Fusion Cagesmentioning

confidence: 99%