Si: As Focal-Plane Array Detection for Fourier Transform Spectroscopic Imaging in the Infrared Fingerprint Region

Lewis, E. Neil; Kidder, Linda H.; Arens, J. F.; Peck, M. C.; Levin, Ira W.

doi:10.1366/0003702971940602

Cited by 32 publications

(18 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Alternatively, the optical aperture may be omitted, and the single detector element can be replaced by an array detector. In this case, the spatial resolution is determined by the size of each individual detector element; spatial resolutions of about 4–10 μm have been achieved 7, 8. Following previous literature, we refer to this methodology as IR spectral imaging .…”

Section: Introductionmentioning

confidence: 99%

Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue

2000

View full text Add to dashboard Cite

Experimental and computational methods of infrared microspectroscopy (IRI‐MSP) and infrared spectral mapping (ISM) are presented. These methods are subsequently applied to the analysis of cirrhotic liver tissue. The sensitivity of infrared spectral mapping toward spectral changes caused by disease will be demonstrated. In addition, the excellent agreement between ISM data and histopathological information will be discussed. © 2000 John Wiley & Sons, Inc. Biopolymers (Biospectroscopy) 57: 282–290, 2000

show abstract

Section: Introductionmentioning

confidence: 99%

Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue

2000

View full text Add to dashboard Cite

show abstract

“…Notable individual systems included a 16 Â 64 liquid helium-cooled, arsenic-doped silicon (Si:As) FPA [59], and a 256 Â 256 MCT FPA [60], but the challenge was to locate an MCT array, and then a camera, and integrate it into a system that could be manufactured in volume, and therefore suitable for a commercial product. Bio-Rad commissioned Santa Barbara Focalplane (SBFP) to produce such a camera.…”

Section: The ''Javelin'' Mct Cameramentioning

confidence: 99%

FT‐IR Imaging Hardware

Sellors

Hoult

Crocombe

et al. 2010

Raman, Infrared, and Near‐Infrared Chemical Imaging

View full text Add to dashboard Cite

The combination of IR spectroscopy with visible microscopy has been used in a wide range of analytical applications for more than 20 years. More recently, however, IR microspectroscopy has benefited from developments in IR detector arrays leading to a marked growth in FT-IR imaging technologies and applications. It is now a fairly simple task to obtain a high-quality IR spectrum from a sample region of around 20 mm in matter of seconds, and the ability to collect full IR images containing hundreds of thousands of pixels, where every image pixel contains a full range IR spectrum, is now available in many hundreds of laboratories worldwide. IR imaging hardware is not yet mature, but despite this, with today's state-of-the-art FT-IR imaging systems, the analysis time for many applications is limited not by the speed at which quality images are obtained, but by the data analysis or sample preparation techniques at the disposal of the operator.Progress in commercial FT-IR imaging hardware development comes from various drivers, but two are particularly relevant: (a) the high popularity of single point IR microscopy systems that has fuelled the interest in technology and applications utilizing more rapid methods of data acquisition and (b) the development of multichannel array detectors that operate in the mid-infrared region for nonspectroscopic applications. These are fundamental to both the understanding of current FT-IR imaging technologies and probable developments in the near future. Developments in IR Microscopy and Imaging SystemsInterest in obtaining IR spectra from small samples goes back to over 60 years; for example, a reported study of the structure of penicillin by Thomson [1] in the late 1940s used a prismbased dispersive spectrometer coupled with a beam condenser/microscope system. A commercial IR microscope system described in 1953 by Coates et al. [2] demonstrated quite respectable IR spectra from single fiber samples of less than 20 mm in diameter, recorded with 15 min scan times, and contained some design attributes that are still present in today's systems. However, it was not until early 1980s when the rapid uptake of commercial FT-IR systems and applications such as semiconductor microanalysis provided both the applications and technology interest to spur the growth in IR microspectroscopy. Today, all major manufacturers of laboratory FT-IR spectrometers include IR microscopes, some with automated point mapping systems, as well as imaging systems in their product portfolios.Early (1980s) FT-IR microscope systems were mostly bolt-on accessories derived from optical microscope frames that were modified to support the collection of IR spectra from selected regions of interest (ROI). Later, systems were Raman, Infrared, and Near-Infrared Chemical Imaging Edited by Slobodan Š ašić and Yukihiro Ozaki

show abstract

“…Several types of IRsensitive materials have been incorporated onto detector arrays; indium antimonide (InSb) and mercury-cadmium-telluride, HgCdTe (MCT), silicon arsenide (Si:As) (33), and barium strontium titanium (BST) (34). Mid-IR imaging using MCT FPAs (35) has been the most popular in terms of number of studies owing to its availability at a moderate cost and, most importantly, ability to access the IR fingerprint region of the spectrum.…”

Section: Global Imaging With Two-dimensional Array Detectorsmentioning

confidence: 99%

FOURIER TRANSFORM INFRARED VIBRATIONAL SPECTROSCOPIC IMAGING: Integrating Microscopy and Molecular Recognition

Levin

Bhargava

2005

Annu. Rev. Phys. Chem.

Self Cite

273

203

View full text Add to dashboard Cite

The recent development of Fourier transform infrared (FTIR) spectroscopic imaging has enhanced our capability to examine, on a microscopic scale, the spatial distribution of vibrational spectroscopic signatures of materials spanning the physical and biomedical disciplines. Recent activity in this emerging area has concentrated on instrumentation development, theoretical analyses to provide guidelines for imaging practice, novel data processing algorithms, and the introduction of the technique to new fields. To illustrate the impact and promise of this spectroscopic imaging methodology, we present fundamental principles of the technique in the context of FTIR spectroscopy and review new applications in various venues ranging from the physical chemistry of macromolecular systems to the detection of human disease.

show abstract

Si: As Focal-Plane Array Detection for Fourier Transform Spectroscopic Imaging in the Infrared Fingerprint Region

Cited by 32 publications

References 20 publications

Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue

Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue

FT‐IR Imaging Hardware

FOURIER TRANSFORM INFRARED VIBRATIONAL SPECTROSCOPIC IMAGING: Integrating Microscopy and Molecular Recognition

Contact Info

Product

Resources

About