Shrimp protected from WSSV disease by treatment with egg yolk antibodies (IgY) against a truncated fusion protein derived from WSSV

Passive protection of shrimp against white spot syndrome virus (WSSV) using specific antibody from egg yolk of chickens immunized with inactivated virus or a WSSV-DNA vaccine

“…Some previous studies have shown that antiserum against VP28 abolished WSSV-induced mortality of Penaeus monodon [10] and cytopathic effects in P. monodon lymphoid organ cells in vitro [13]. In addition, antibodies against VP28 and fusion proteins comprising portions of VP28 and VP19 have successfully neutralized WSSV [14,15].…”

Protection of Procambarus clarkii against white spot syndrome virus using recombinant oral vaccine expressed in Pichia pastoris

“…Li et al [32] has reported 100% and 35% RPS values when VP19 þ VP28 antiserum had been used as vaccine component at 15e22 C and 26 C respectively. Kim et al [31] obtained 85% survivability when treated with egg yolk antibodies. The better performance vaccine groups containing reVP28Y agrees with Van Hulten et al [9,10], which states that VP28 plays major role in the systemic infection of crustaceans using as in vitro neutralisation strategies.…”

Passive Immunization of Crayfish (Procambius clarkiaii) with Chicken Egg Yolk Immunoglobulin (IgY) Against White Spot Syndrome Virus (WSSV)

“…Kim et al used protein vaccine, recombinant protein, to obtain IgY antibody, which could neutralize or show antiviral activity [8]. As we all know, the DNA vaccine has some advantages since it allows rapid design of a vaccine that contains immunologically reactive sequence without a procedure of protein expression and purification.…”

“…However, only one study described the effect of IgY in crustaceans. Kim et al showed that IgY has a potential for immunotherapeutic application to prevent WSSV infection in shrimp (P. chinensis) [8].…”