Short-Term Treatment Results for Unilateral Vocal Fold Palsy Induced by Mediastinal Lesions

Lee, Yoon Se; Kim, Yong Hee; Kwon, Minsu; Ryu, In Sun; Jung, G.-U.; Kim, Seong-Tae; Roh, Jong–Lyel; Choi, Seung-Ho; Kim, Sang Yoon; Nam, Soon-Yuhl

doi:10.1016/j.jvoice.2014.04.003

Cited by 7 publications

(5 citation statements)

References 35 publications

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“…However, it was possible to completely resect the lymph node metastasis, and until today, there has been no local recurrence in this region. So far, none of the three patients have developed an intrathoracic tumor recurrence, thereby avoiding local complications, such as recurrent nerve involvement [26,27], dyspnea, infection, or hemoptysis. In our opinion, this also speaks in favor of a surgical approach.…”

Section: Discussionmentioning

confidence: 98%

Pulmonary Resection after Radiosurgery and Neoadjuvant Immunochemotherapy for NSCLC Patients with Synchronous Brain Metastasis—A Case Series of Three Patients

et al. 2022

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Brain metastases are a common finding upon initial diagnosis of otherwise locally limited non-small cell lung cancer. We present a retrospective case series describing three cases of patients with symptomatic, synchronous brain metastases and resectable lung tumors. The patients received local ablative treatment of the brain metastases followed by neoadjuvant immunochemotherapy with pemetrexed, cisplatin, and pembrolizumab. Afterwards, resection of the pulmonary lesion with curative intent was performed. One patient showed progressive disease 12 months after initial diagnosis, and passed away 31 months after initial diagnosis. Two of the patients are still alive and maintain a good quality of life with a progression-free survival and overall survival of 28 and 35 months, respectively, illustrating the potential of novel combinatorial treatment approaches.

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Section: Discussionmentioning

confidence: 98%

Pulmonary Resection after Radiosurgery and Neoadjuvant Immunochemotherapy for NSCLC Patients with Synchronous Brain Metastasis—A Case Series of Three Patients

et al. 2022

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“…Vocal cord palsy induced by mediastinal lesion or surgery tends to lead to larger glottis gap as compared to injury from thyroidectomy 1 . It is seen in this case whereby the left vocal cord palsy was not compensated by the normally functioning right side.…”

Section: Discussionmentioning

confidence: 99%

“…Besides neck trauma and iatrogenic damage to the intact nerve during surgery to the thyroid or mediastinum, the presence of any lesion along the course of the recurrent laryngeal nerve can results in direct compression or invasion to the neural integrity 1 . The left side is more common to be affected owing to its longer course.…”

Section: Introductionmentioning

confidence: 99%

Unilateral vocal cord palsy as the presentation of metastatic mediastinal adenocarcinoma

Mohamad

Nadarajan

Win

2018

Bangladesh J Med Sci

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Introduction: Unilateral vocal cord palsy is more common than the bilateral cases. The left side is more affected than the right side owing the longer course of the Left recurrent laryngeal nerve. Iatrogenic causes for example thyroidectomy or cardiac surgery predominate the etiology of its incidence. Methods: A review of medical case record. Results: A 68-year-old man presented with voice change for one month duration. It was associated with occasional shortness of breath. Examination showed unilateral Left vocal cord palsy. Further investigation revealed a huge anterior mediastinal mass. A CT-guided biopsy was performed and histopathologically confirmed as adenocarcinoma. Conclusion: Any lesion in the course of recurrent laryngeal nerve can lead to vocal cord palsy and change of voice. A metastatic lesion to mediastinal nodes even though very rare can be one of them. Mediastinal lymphoma is one of its differential diagnoses.

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“…Unilateral vocal fold paralysis (UVFP) is a frequent complication of surgical manipulation of the thyroid gland and mediastinal structures, which are located along the pathway of the recurrent laryngeal nerve [1][2][3] . Less than 50% of cases of vocal fold immobility caused by injury during surgery recover spontaneously within one year, while the remaining patients show persistent UVFP 1 . A growing number of idiopathic UVFP is documented [2][3][4] .…”

Section: Introductionmentioning

confidence: 99%

Efficacy of trans-nasal fiberendoscopic injection laryngoplasty with centrifuged autologous fat in the treatment of glottic insufficiency due to unilateral vocal fold paralysis

Maccarini

Stacchini

Mozzanica

et al. 2018

Acta Otorhinolaryngol Ital

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Short-Term Treatment Results for Unilateral Vocal Fold Palsy Induced by Mediastinal Lesions

Cited by 7 publications

References 35 publications

Pulmonary Resection after Radiosurgery and Neoadjuvant Immunochemotherapy for NSCLC Patients with Synchronous Brain Metastasis—A Case Series of Three Patients

Pulmonary Resection after Radiosurgery and Neoadjuvant Immunochemotherapy for NSCLC Patients with Synchronous Brain Metastasis—A Case Series of Three Patients

Unilateral vocal cord palsy as the presentation of metastatic mediastinal adenocarcinoma

Efficacy of trans-nasal fiberendoscopic injection laryngoplasty with centrifuged autologous fat in the treatment of glottic insufficiency due to unilateral vocal fold paralysis

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