Short-term outcome of critically ill patients with severe acute respiratory syndrome

Abstract

Mortality amongst critically ill patients with SARS is high. It causes predominantly severe respiratory failure, with little other organ failure, and a high incidence of barotrauma amongst those requiring mechanical ventilation.

Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission

“…In fact, SARS-CoV was associated with a wide spectrum of clinical features-infected people presented initially with fever, myalgia, chills, and rigor and subsequently developed pneu monia. 14,18 Notably, patient 1 had diarrhoea among initial symptoms, a feature not yet reported in patients with MERS-CoV, but present upon admission in a quarter of patients with SARS. 19 Patient 1 died on May 28, and patient 2 remains in the ICU under ECMO.…”

Severe Acute Respiratory Syndrome

“…32 Despite the use of lung protective IMV with a low tidal volume, barotrauma occurred in 26% of critically ill cases of SARS-CoV infection, possibly owing to decreased lung compliance. 81…”

Clinical management and infection control of SARS: Lessons learned

“…The radiographic features of SARS were similar to viral pneumonia, but ground-glass opacities and focal consolidations as demonstrated in chest radiographs predominantly involved the peripheral and subpleural regions of the lower zones (Grinblat et al, 2003;Hsieh et al, 2004;Lai et al, 2005a). Spontaneous pneumomediastium was found in about 12% of cases , whereas 26% of patients developed barotrauma during mechanical ventilation (Gomersall et al, 2004).…”