Short-Term Intellectual Outcome After Arterial Ischemic Stroke and Sinovenous Thrombosis in Childhood and Infancy

Abstract

Arterial ischemic stroke is approximately four times more prevalent than sinovenous thrombosis and has been associated with a worse neurologic outcome than sinovenous thrombosis; however, no data are available comparing intellectual outcome after pediatric arterial ischemic stroke and sinovenous thrombosis. We report the short-term intellectual outcome (mean 5.8 months since stroke) in a sample of 72 children, 47 with arterial ischemic stroke, and 25 with sinovenous thrombosis. Intellectual outcome measures were the Full-Scale IQ of the age-appropriate Wechsler intelligence test for older children and the Mental Developmental Index of the Bayley Scales of Infant Development for younger children. Stroke type did not directly influence intellectual outcome. Intellectual outcome was in the normal range whether the children had suffered an arterial ischemic stroke or a sinovenous thrombosis.

Factors affecting cognitive outcome in early pediatric stroke

“…Moreover, due to our prospective study design and lack of intelligence measures for the youngest age group, it was necessary to include a developmental measure as an outcome measure. However, taking into account the result of a previous study, 38 which did not find any age at stroke effect, although their youngest age group was exclusively tested with the BSID-II, we argue that our finding that the early age group showed the worst cognitive outcome cannot solely be due to the use of the BSID-II. Moreover, the youngest children in our study with NI and a low cognitive outcome might be prone to a "growing into deficit" and therefore may have increasingly significant cognitive deficits with time.…”

Hemorrhagic Stroke in Children

“…Neurologic outcome after childhood arterial ischemic stroke has been reported by several groups [67][68][69]. Outcome after HS, however, has not been well studied in children.…”

Outcome in Childhood Stroke

“…The majority of studies reporting cognitive 26,39,40 and functional 41,42 outcomes after childhood stroke have not assessed the influence of risk factors or pathogenesis on outcome. A recent Swiss multicentre study, however, found no association between risk factors and cognition.…”