Short-term evaluation of the pulpo-dentin complex response to a resin-modified glass-ionomer cement and a bonding agent applied in deep cavities

Costa, Carlos Alberto de Souza; Giro, Elisa María Aparecida; Nascimento, Alexandre Batista Lopes do; Teixeira, Hilcia Mezzalira; Hebling, Josimeri

doi:10.1016/s0109-5641(03)00021-6

Cited by 90 publications

(24 citation statements)

References 24 publications

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“…The pulpal response results provided the necessary in vivo evidence to support our claim that the use of the augmented-pressure adhesive displacement technique does not generate a strong negative capillary pressure that causes displacement of odontoblast cell bodies into the dentinal tubules. It is important to highlight that tooth preparation and bonding treatment can induce transient pulp inflammation294445. Findings of the present work are in agreement with those studies.…”

Section: Discussionsupporting

confidence: 92%

Caries-resistant bonding layer in dentin

Zhou¹,

Niu

et al. 2016

Sci Rep

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The present study examined the mechanism for caries resistance and the pulp responses in vital teeth following the use of the augmented-pressure adhesive displacement technique. Dentin adhesives were applied to the surface of sound dentin disks in 4 experimental groups: non-antibacterial adhesive and gentle adhesive displacement (N-G), non-antibacterial adhesive and augmented-pressure adhesive displacement (N-H), antibacterial adhesive and gentle adhesive displacement (A-G), antibacterial adhesive and augmented-pressure adhesive displacement (A-H). The depth of demineralization induced by biological or chemical demineralization models was measured using confocal laser scanning microscopy and analyzed with two-way ANOVA. Pulp responses of vital dog’s teeth to the augmented-pressure adhesive displacement technique were evaluated using light microscopy. Depth of demineralization was significantly affected by “adhesive type” and “intensity of adhesive displacement” for biological demineralization. For chemical demineralization, only “intensity of adhesive displacement” showed significant influence on lesion depth. Pulp response of 0.1, 0.2 and 0.3 MPa groups showed only moderate disorganization of the odontoblast layer at 24 hours that completely re-organized after 3 weeks. Augmented-pressure adhesive displacement improves the caries resistance property of bonded dentin and does not cause irreversible pulpal damage to vital teeth when the air pressure employed is equal or smaller than 0.3 MPa.

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Section: Discussionsupporting

confidence: 92%

Caries-resistant bonding layer in dentin

Zhou¹,

Niu

et al. 2016

Sci Rep

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“…Cavity preparation induces a pulp reaction that depends on several factors, including mechanical and thermal irritation, injury to the odontoblastic process, remaining dentin thickness and toxicity of subsequent dental materials like luting cements (2,8,16). …”

Section: Discussionmentioning

confidence: 99%

“…Continuous development of dental products has provided a wide range of biomaterials to deal with various clinical conditions in dentistry. However, despite these improvements, there is still a need for a biomaterial that completely fulfills all the requirements for a cementing agent, including high biocompatibility, antimicrobial effect, good mechanical properties and to generate appropriate pulpal response (2). …”

Section: Introductionmentioning

confidence: 99%

“…The biological effect of luting cements seems to be controversial in the literature, as there are reports that postoperative sensitivity is a common consequence with the use of resin-based cements, while others report excellent biocompatibility when the cavity is not very deep (2,3). Moreover, an in vivo experiment showed that resin modified glass ionomer cements applied in deep class V cavities generate mild to moderate inflammatory reactions in short (3 to 7 days) experimental periods (8).…”

Section: Introductionmentioning

confidence: 99%

“…However, little is known about SP behavior in response to the application of luting cements over dentin. Previous research has focused on describing cellular and histological inflammatory changes in pulp produced by these cements (2,7,8) but there is no evidence to date on the effect of these cements over SP release.…”

Section: Introductionmentioning

confidence: 99%

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The effect of glass ionomer and adhesive cements on substance P expression in human dental pulp

Caviedes-Bucheli¹,

Ariza-García²,

Camelo³

et al. 2013

Med Oral

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Objectives: The purpose of this study was to quantify the effect of glass ionomer and adhesive cements on SP expression in healthy human dental pulp. Study Design: Forty pulp samples were obtained from healthy premolars where extraction was indicated for orthodontic reasons. In thirty of these premolars a Class V cavity preparation was performed and teeth were equally divided in three groups: Experimental Group I: Glass Ionomer cement was placed in the cavity. Experimental Group II: Adhesive Cement was placed in the cavity. Positive control group: Class V cavities only. The remaining ten healthy premolars where extracted without treatment and served as a negative control group. All pulp samples were processed and SP was measured by radioimmunoassay. Results: Greater SP expression was found in the adhesive cement group, followed by the glass ionomer and the positive control groups. The lower SP values were for the negative control group. ANOVA showed statistically significant differences between groups (p<0.0001). Tukey HSD post hoc tests showed statistically significant differences in SP expression between negative control group and the 3 other groups (p<0.01). Differences between the cavity-only group and the two experimental groups were also statistically significant (p<0.05 and p<0.01 respectively). There is also a statistically significant difference between the two experimental groups (p<0.01). Conclusions: These findings suggest that adhesive cements provoke a greater SP expression when compared with glass ionomer. Key words:Glass Ionomer, adhesive cement, Substance P, human dental pulp.

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