2013
DOI: 10.1093/eurheartj/eht489
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Short-term effects of air pollution on out-of-hospital cardiac arrest in Stockholm

Abstract: Short-term exposure to moderate levels of O3 is associated with an increased risk of OHCA.

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Cited by 90 publications
(60 citation statements)
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“…Arrhythmia is the common cause for sudden cardiac deaths. However, among eight studies investigating the impact of NO 2 on OHCAs [2,3,[5][6][7][8][9][10], only one identified positive associations [2]. In our study, increased NO 2 significantly raised the OHCA risk at lag 0 and lag 1 but not at lag 2-lag 6 days, indicating a rapid effect of short-term NO 2 exposure on precipitating OHCAs.…”
contrasting
confidence: 59%
“…Arrhythmia is the common cause for sudden cardiac deaths. However, among eight studies investigating the impact of NO 2 on OHCAs [2,3,[5][6][7][8][9][10], only one identified positive associations [2]. In our study, increased NO 2 significantly raised the OHCA risk at lag 0 and lag 1 but not at lag 2-lag 6 days, indicating a rapid effect of short-term NO 2 exposure on precipitating OHCAs.…”
contrasting
confidence: 59%
“…[2][3][4][5][6][7][8][9][10][11] Our results were most robust for NO x , which remained associated with cardiovascular event risk even after accounting for unmeasured confounders and even showed some association after adjusting for other pollutants. However, we note that while performing multipollutant analyses is common practice within environmental epidemiology, the results should be interpreted cautiously, as the interpretation requires holding all other pollutants fixed, which may not be realistic for teasing out the 'independent' pollutant effect.…”
Section: Discussionmentioning
confidence: 54%
“…1 Increased risk of non-fatal cardiovascular or cerebrovascular events is seen with exposure to particulate matter with aerodynamic diameter <10 μm (PM 10 ) and <2.5 μm (PM 2.5 ), nitrogen oxide (NO x ), ozone, carbon monoxide (CO) and sulfur dioxide (SO 2 ). [2][3][4][5][6][7][8][9][10][11] Some subpopulations may be particularly sensitive to air pollution exposure, such as the elderly, diabetics and persons with obesity or existing cardiac disease. 12 13 Given the physiological changes in pregnancy, including increased oxygen requirements and cardiac output, elevation in plasma volume, changes in vascular resistance and blood pressure, hypercoagulability and higher risk of acute myocardial infarcts, 14 15 we hypothesise that air pollution may be associated with increased risk for maternal cardiovascular events during or immediately after labour and delivery.…”
Section: Introductionmentioning
confidence: 99%
“…Previous studies have not investigated shorter time frames of temperature exposure than 24 h. OHCAs and their underlying ventricular tachyarrhythmias have been found to be triggered by hourly exposure to ozone (Raza et al, 2014) and particulate matter (Ljungman et al, 2008;Rich et al, 2006). We therefore made use of our high temporal resolution of OHCA debut to investigate very short-term triggering.…”
Section: Discussionmentioning
confidence: 99%