Short-term effect of transcatheter aortic valve implantation on QT dispersion

Kasapkara, Hacı Ahmet; Ayhan, Hüseyin; Durmaz, Tahir; Keleş, Telat; Sarı, Cenk; Baştuğ, Serdal; Köseoğlu, Cemal; Karaduman, Bilge Duran; Akçay, Murat; Bayram, Nihal Akar; Bilen, Emine; Bozkurt, Engin

doi:10.3906/sag-1402-49

Cited by 5 publications

(4 citation statements)

References 20 publications

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“…Several studies have shown that QTd increased in patients with AS [15] and the increased QTd value significantly reduced after TAVI. [16,17] Similar to these studies, we also found significant reductions in QT, QTc, and QTd after three months from TAVI. However, in these studies, only QT parameters were used, and no information about the novel repolarization markers.…”

Section: Discussionsupporting

confidence: 86%

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The effect of transcatheter aortic valve implantation on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios, and Tp-e dispersion in patients with severe aortic stenosis

Tanriverdi

Colluoglu

Ünal

et al. 2018

Turk Gogus Kalp Dama

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Bu çalışmada iki farklı biyoprotez kapak ile yapılan transkateter aort kapak implantasyonunun Tp-e, Tp-e/QT ve Tpe/QTc oranları ve Tp-ed gibi yeni ventriküler repolarizasyon belirteçleri üzerindeki etkisi incelendi.Ça lış mapla nı:Medtronic CoreValve (n=40) veya Edwards SAPIEN XT (n=21) kapak ile transkateter aort kapak implantasyonu yapılan toplam 61 hasta (17 erkek, 44 kadın; ort. yaş 78.6±6.5 yıl; dağılım 55-89 yıl) retrospektif olarak incelendi. Elektrokardiyografik parametreler ve sol ventrikül kütle indeksi işlemden önce, işlemden bir gün sonra ve işlemden sonra üçüncü ayda hesaplandı. Bul gu lar:Tp-e aralığı, Tp-e/QT ile Tp-e/QTc oranları, Tp-ed ve sol ventrikül kütle indeksi başlangıç değerlerine kıyasla, işlemin üçüncü ayında anlamlı ölçüde azaldı (tümü için p<0.01). Benzer bulgular QT, QTc ve QT dispersiyonu için gözlendi (tümü için p<0.01). Bu değişiklikler, kullanılan biyoprotez kapak türlerinden bağımsızdı. İşlem öncesinde, sol ventrikül kütle indeksi Tp-e (r= 0.350, p= 0.007), Tp-e/QT (r= 0.314, p= 0.015) ve Tp-e/QTc oranları (r= 0.285, p= 0.029) ile pozitif şekilde ilişkili idi. Çok değişkenli analizde, Tp-e aralığı ile sol ventrikül kütle indeksi arasında bağımsız bir ilişki tespit edildi (b= 0.350, p= 0.007). So nuç:Bu çalışmada Tp-e aralığı, Tp-e/QT ile Tp-e/QTc oranları, Tp-ed ve sol ventrikül kütle indeksi transkateter aort kapak implantasyonundan üç ay sonra anlamlı şekilde azalarak, sol ventrikülün yeniden yapılanmasını gösterdi. İki biyoprotez kapağın ventriküler repolarizasyon belirteçleri ve sol ventrikül kütle indeksi üzerindeki etkisi benzerdi.Anah tar söz cük ler: Aort kapak darlığı; elektrokardiyografi; kalp kapak protezi; ventriküler repolarizasyon belirteçleri.

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Section: Discussionsupporting

confidence: 86%

“…[14] Several studies showed that QTd (QT dispersion) increased in patients with AS, while TAVI was found to cause a significant reduction in QTd. [15][16][17] In addition, Tp-e interval, Tp-e/QT, and Tp-e/QTc ratios were shown to increase in patients with severe AS. [18] However, there is no study investigating the effect of TAVI on these novel markers.…”

mentioning

confidence: 99%

The effect of transcatheter aortic valve implantation on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios, and Tp-e dispersion in patients with severe aortic stenosis

Tanriverdi

Colluoglu

Ünal

et al. 2018

Turk Gogus Kalp Dama

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“…QTD is increased in most patients with AS and these changes are weakly related to the degree of left ventricular hypertrophy [4]. Several studies have shown that increased QTD due to AS, which is associated with the risk of ventricular arrhythmia, decreases after TAVI [7,10]. Our findings also confirmed that prolonged QTD and QTcD rapidly decline after TAVI treatment, whereas SAVR slowly recovers QTD and QTcD.…”

Section: Comparison Of Qtd Between Tavi and Savrsupporting

confidence: 84%

“…The prolongation of the interval from the peak to the end of the T wave (Tpeak-Tend: TpTe) on ECG and TpTe/QT ratio, which reflects the transmural dispersion of ventricular repolarization (TDR), has also been associated with the incidence of ventricular arrhythmia [6,7]. Similar to QTD, TpTe is prolonged in patients with severe AS and immediately recovers after TAVI [8].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Cardiac Repolarization After Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement: A Longitudinal Study

et al. 2019

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Introduction: Transcatheter aortic valve implantation (TAVI) has been established as an alternative to surgical aortic valve replacement (SAVR) for high-risk patients. To assess the impact of TAVI on cardiac repolarization, we compared QT dispersion (QTD) and the interval from the peak to the end of the T wave (Tpeak-Tend: TpTe) between the patients who underwent TAVI and those who underwent SAVR and TpTe between the patients who underwent TAVI or SAVR. Methods: This retrospective study was approved by the ethics committee of Dokkyo Medical University Hospital. The study included 45 patients who underwent TAVI and 45 patients who underwent SAVR. The QT, corrected QT (QTc), QTD, QTc dispersion (QTcD), Tp-Te, Tp-Te/QT, and Tp-Te/QTc were manually measured in standard 12-lead electrocardiogram (ECG) recordings obtained before surgery, immediately after surgery, 1 month, 3 months, and 6 months after surgery and compared between the two groups. Results: No change was observed in RR, QT, QTc, Tp-Te, Tp-Te/QT, and Tp-Te/QTc in the two groups throughout the study. The QTD and QTcD significant decreased immediately after surgery in the TAVI group as compared to the SAVR group (P \ 0.001). In contrast, QTD and QTcD in the SAVR group gradually, but not significantly declined 6 months after surgery. Conclusions: QTD and QTcD immediately decreased after TAVI as compared to SAVR. Our findings indicate that TAVI more rapidly improved dispersion of spatial repolarization than SAVR.

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Evaluation of Tp-e interval, Tp-e/QT and Tp-e/QTc ratio in aortic valve stenosis before and after transcatheter aortic valve implantation

Kahraman

Doğan

Kalkan

et al. 2018

Journal of Electrocardiology

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Short-term effect of transcatheter aortic valve implantation on QT dispersion

Cited by 5 publications

References 20 publications

The effect of transcatheter aortic valve implantation on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios, and Tp-e dispersion in patients with severe aortic stenosis

The effect of transcatheter aortic valve implantation on Tp-e interval, Tp-e/QT and Tp-e/QTc ratios, and Tp-e dispersion in patients with severe aortic stenosis

Comparison of Cardiac Repolarization After Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement: A Longitudinal Study

Evaluation of Tp-e interval, Tp-e/QT and Tp-e/QTc ratio in aortic valve stenosis before and after transcatheter aortic valve implantation

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