Short‐term complications and post‐acute sequelae in hospitalized paediatric patients with <scp>COVID</scp>‐19 and obesity: A multicenter cohort study

Valenzuela, Gonzalo; Alarcón-Andrade, Gonzalo; Schulze, Clara; Rodríguez, Rocío; García-Salum, Tamara; Pardo-Roa, Catalina; Lévican, Jorge; Serrano, Eileen; Avendaño, María José; Gutiérrez, Monserrat; Godoy, Loreto; Céspedes, Pamela; Bermúdez, Sandra; Aravena, Javiera; Nicolaides, Irini; Martinez, Eliana C.; Gómez-Canobbio, Constanza; Jofré, Macarena; Salinas, Andrea; Depaoli, Daniela; Loza, Carolina; Muñoz, A Pablo; Ormazábal, Natalia; Manzur, Diana; Barriga, Jose; Almonacid, Leonardo; Poblete-Cárdenas, Estefany; Salinas, Erick; Muñoz-Marcos, Andrés; Barja, Salesa; Medina, Rafael

doi:10.1111/ijpo.12980

Cited by 5 publications

(3 citation statements)

References 43 publications

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“…These include older age, increased body mass index, and allergic diseases 22,24,45,53 . In particular, links between excessive weight and obesity and severe short‐term outcomes and postacute sequelae have been recognized 22,36,54 . In keeping with these reports, in our study group, we noticed pulmonary impairment in teenagers with obesity.…”

Section: Discussionsupporting

confidence: 87%

“…22,24,45,53 In particular, links between excessive weight and obesity and severe short-term outcomes and postacute sequelae have been recognized. 22,36,54 In keeping with these reports, in our study group, we noticed pulmonary impairment in teenagers with obesity. However, our results cannot be directly compared to those presented above as we included only patients with COVID-19 pneumonia (irrespective of prolonged symptoms).…”

Section: While Increasing Number Of Studies Assessing Children After ...supporting

confidence: 91%

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The outcomes of COVID‐19 pneumonia in children—clinical, radiographic, and pulmonary function assessment

Bogusławski

Strzelak

Gajko

et al. 2023

Pediatric Pulmonology

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Objectives The goal of this study was to assess the pulmonary sequelae of COVID‐19 pneumonia in children. Study Design Children (0–18 years old) diagnosed with COVID‐19 pneumonia hospitalized between March 2020 and March 2021 were included in this observational study. All children underwent follow‐up visits 3 months postdischarge, and if any abnormalities were stated, a second visit after the next 3 months was scheduled. Clinical assessment included medical history, physical examination, lung ultrasound (LUS) using a standardized protocol, and pulmonary function tests (PFTs). PFTs results were compared with healthy children. Results Forty‐one patients with COVID‐19 pneumonia (severe disease n = 3, mechanical ventilation, n = 0) were included in the study. Persistent symptoms were reported by seven (17.1%) children, the most common was decreased exercise tolerance (57.1%), dyspnea (42.9%), and cough (42.9%). The most prevalent abnormalities in LUS were coalescent B‐lines (37%) and small subpleural consolidations (29%). The extent of LUS abnormalities was significantly greater at the first than at the second follow‐up visit (p = 0.03). There were no significant differences in PFTs results neither between the study group and healthy children nor between the two follow‐up visits in the study group. Conclusions Our study shows that children might experience long‐term sequelae following COVID‐19 pneumonia. In the majority of cases, these are mild and resolve over time.

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Section: Discussionsupporting

confidence: 87%

Section: While Increasing Number Of Studies Assessing Children After ...supporting

confidence: 91%

The outcomes of COVID‐19 pneumonia in children—clinical, radiographic, and pulmonary function assessment

Bogusławski

Strzelak

Gajko

et al. 2023

Pediatric Pulmonology

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“…Available findings and knowledge regarding LC sequelae are limited. Evidence in children and adolescents has indicated that obesity is associated with the severity of LC sequelae (235). LC-related symptoms were associated with a change in body weight that was independent of the patient's initial COVID-19 status (236).…”

Section: Obesity and Covid-19mentioning

confidence: 99%

Sequelae of long COVID, known and unknown: A review of updated information

Asakawa

Cai

Shen

et al. 2023

BST

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Over three years have passed since the COVID-19 pandemic started. The dangerousness and impact of COVID-19 should definitely not be ignored or underestimated. Other than the symptoms of acute infection, the long-term symptoms associated with SARS-CoV-2 infection, which are referred to here as "sequelae of long COVID (LC)", are also a conspicuous global public health concern. Although such sequelae were well-documented, the understanding of and insights regarding LC-related sequelae remain inadequate due to the limitations of previous studies (the follow-up, methodological flaws, heterogeneity among studies, etc.). Notably, robust evidence regarding diagnosis and treatment of certain LC sequelae remain insufficient and has been a stumbling block to better management of these patients. This awkward situation motivated us to conduct this review. Here, we comprehensively reviewed the updated information, particularly focusing on clinical issues. We attempt to provide the latest information regarding LC-related sequelae by systematically reviewing the involvement of main organ systems. We also propose paths for future exploration based on available knowledge and the authors' clinical experience. We believe that these take-home messages will be helpful to gain insights into LC and ultimately benefit clinical practice in treating LC-related sequelae.

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COVID-19 related ICU admissions in paediatric and young adult patients in Australia: a national case series 2020–2022

Otto¹,

Britton²,

Neto³

et al. 2023

The Lancet Regional Health - Western Pacific

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Short‐term complications and post‐acute sequelae in hospitalized paediatric patients with COVID‐19 and obesity: A multicenter cohort study

Cited by 5 publications

References 43 publications

The outcomes of COVID‐19 pneumonia in children—clinical, radiographic, and pulmonary function assessment

The outcomes of COVID‐19 pneumonia in children—clinical, radiographic, and pulmonary function assessment

Sequelae of long COVID, known and unknown: A review of updated information

COVID-19 related ICU admissions in paediatric and young adult patients in Australia: a national case series 2020–2022

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