“…However, safety and acceptability should be assessed with consolidated and comparable methodologies to rule out risks in use [ 37 – 39 ]. (ii) Satisfaction, intended as a usability metric, is a different construct from acceptability, and these two constructs should be measured separately with available standardized questionnaires [ 39 , 40 ]. (iii) Although dedicated tools and methods for assessing the quality of interaction with chatbots are lacking, reliable methods and measures to assess interaction are available [ 17 , 19 , 21 , 37 ], and these should be adopted and used to enable the generation of comparable evidence regarding the quality of conversational agents.…”