volume 6, issue 5, P414-427 2014
DOI: 10.18632/aging.100671
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Shufeng Chen, Jue Lin, Tet Matsuguchi, Elizabeth Blackburn, Fawn Yeh, Lyle G. Best, Richard B. Devereux, Elisa T. Lee, Barbara V. Howard, Mary J. Roman, Jinying Zhao

Abstract: Short leukocyte telomere length (LTL) has been associated with atherosclerosis in cross-sectional studies, but the prospective relationship between telomere shortening and risk of developing carotid atherosclerosis has not been well-established. This study examines whether LTL at baseline predicts incidence and progression of carotid atherosclerosis in American Indians in the Strong Heart Study. The analysis included 2,819 participants who were free of overt cardiovascular disease at baseline (2001-2003) and w…

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