Short duration general anaesthesia in the horse using guaiacol glycerine ether and thiopentone sodium

Brouwer, G.J.

doi:10.1111/j.2042-3306.1985.tb02488.x

Cited by 5 publications

(3 citation statements)

References 9 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Guaiphenesin has a wide margin of safety and its sedative properties are potentiated by combination with sedative drugs (Schatzmann 1974; Schatzmann et al. 1978; Brouwer 1985).…”

Section: Discussionmentioning

confidence: 99%

Anaesthesia in horses using halothane and intravenous ketamine–guaiphenesin: a clinical study

Spadavecchia

Stucki

Moens

et al. 2002

Veterinary Anaesthesia and Analgesia

View full text Add to dashboard Cite

“…Guaiphenesin has a wide margin of safety and its sedative properties are potentiated by combination with sedative drugs (Schatzmann 1974; Schatzmann et al. 1978; Brouwer 1985).…”

Section: Discussionmentioning

confidence: 99%

Anaesthesia in horses using halothane and intravenous ketamine–guaiphenesin: a clinical study

Spadavecchia

Stucki

Moens

et al. 2002

Veterinary Anaesthesia and Analgesia

View full text Add to dashboard Cite

“…Guaiphenesin has been used during induction to anaesthesia combined with barbiturates (Brouwer 1985) and with xylazine and ketamine (Muir et a/. 1978) before inhalational anaesthesia.…”

Section: Introductionmentioning

confidence: 99%

The effect of guaiphenesin on romifidine/ketamine anaesthesia in ponies

Walsh

Brearley

Lakhani

et al. 1999

Journal of Veterinary Anaesthesia

View full text Add to dashboard Cite

“…Thiopental and guaifenesin are used to induce general anesthesia in horses undergoing surgery [2,14]. Several studies have reported that induction with thiopental/guaifenesin is particularly smooth and uneventful [2,6,9]. In reference to those reports, Thoroughbred racehorses undergoing arthroscopic surgery at the Japan Racing Association (JRA) racehorse clinics are routinely induced with thiopental/ guaifenesin.…”

mentioning

confidence: 99%

A retrospective comparison of induction with thiopental/guaifenesin and propofol/ketamine in Thoroughbred racehorses anesthetized with sevoflurane and medetomidine during arthroscopic surgery

Tokushige

Araki

Kusano

et al. 2019

JES

View full text Add to dashboard Cite

This study compares clinical characteristics between induction with thiopental/guaifenesin and propofol/ketamine in Thoroughbred racehorses anesthetized with sevoflurane and medetomidine. Clinical records of 214 horses that underwent arthroscopic surgery between 2015 and 2016 were retrospectively retrieved. Horses were premedicated with medetomidine and midazolam to sedate at the adequate level for smooth induction, and then induced with either thiopental (4.0 mg/kg) and guaifenesin (100 mg/kg) in Group TG (n=91) or propofol (1.0 mg/kg) and ketamine (1.0 mg/kg) in Group PK (n=123). Anesthesia was maintained using sevoflurane with constant rate infusion of medetomidine. Quality of induction/recovery, sevoflurane requirement, cardiovascular function and recovery characteristics were evaluated. Anesthetic induction scores (median, range) for Group TG (5, 2–5) and Group PK (5, 2–5) were not significantly different. There were no significant differences in end-tidal sevoflurane concentration (mean ± standard deviation) between Group TG and Group PK (both 2.4 ± 0.2%). Dobutamine infusion rate (µg/kg/min) required for keeping mean arterial blood pressure (MAP) above 70 mmHg in Group PK (0.43, 0.10–1.40) was significantly lower than in Group TG (0.67, 0.08–1.56). Recovery score in Group PK (5, 2–5) was significantly higher than in Group TG (4, 2–5). Both propofol/ketamine and thiopental/guaifenesin provided a smooth induction of anesthesia. Moreover, induction with propofol/ketamine resulted in lower dobutamine requirements for keeping MAP above 70 mmHg during maintenance, and better quality of recovery. Induction with propofol/ketamine would be preferable to thiopental/guaifenesin in Thoroughbred racehorses anesthetized with sevoflurane and medetomidine during arthroscopic surgery.

show abstract

Short duration general anaesthesia in the horse using guaiacol glycerine ether and thiopentone sodium

Cited by 5 publications

References 9 publications

Anaesthesia in horses using halothane and intravenous ketamine–guaiphenesin: a clinical study

Anaesthesia in horses using halothane and intravenous ketamine–guaiphenesin: a clinical study

The effect of guaiphenesin on romifidine/ketamine anaesthesia in ponies

A retrospective comparison of induction with thiopental/guaifenesin and propofol/ketamine in Thoroughbred racehorses anesthetized with sevoflurane and medetomidine during arthroscopic surgery

Contact Info

Product

Resources

About