Shiitake Mushroom Dermatitis

Carlson, Sean; Stuckert, Joseph; Nedorost, Susan T.

doi:10.2310/6620.2010.10040

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…). Twenty‐nine articles were included, comprising a total of 50 cases of patients with shiitake dermatitis . Articles consisted of case reports (24 patients) and case series (26 patients).…”

Section: Resultsmentioning

confidence: 99%

Clinical features of shiitake dermatitis: a systematic review

et al. 2017

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Shiitake dermatitis is a rare cutaneous reaction to lentinan, a polysaccharide component in the cell walls of shiitake mushrooms (Lentinula edodes). Herein, we systematically review the case report and case series English-language literature on shiitake dermatitis, which refers to a total of 50 patients (38 males, 12 females; mean age: 44.58 years). The majority of cases occurred after the consumption of raw mushrooms, whereas 22% of cases were caused by the eating of lightly or undercooked mushrooms. The most common clinical presentations, localized symptoms, and systemic findings include linear flagellated dermatitis (98%), pruritus (78%), and fever, diarrhea, and mucosal ulcers, respectively. The diagnosis of this entity continues to be based on clinical findings as laboratory abnormalities, and the findings of skin biopsies and patch/prick tests are nonspecific and inconsistent. The condition is self-limiting, resolving in approximately 12.5 d without treatment. Based on the included case reports, it appears that medical treatment may slightly shorten the course of disease (to 9-11 d, varying by therapy) but should be considered on an individual patient basis. However, the treatment of symptoms, reassurance, and the avoidance of re-exposure are sufficient treatment recommendations for this condition.

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