Shifting trends of lung tumours and its diagnosis by lung biopsy: a study of 78 cases

Naik, Kinnari; Jarag, Mayur; Shah, Pinal; Patel, Mubin; Patel, Archana; Shah, A.C.

doi:10.18203/2320-6012.ijrms20151392

Cited by 1 publication

(5 citation statements)

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“…When comparing the characteristics of the lung cancer cases, squamous cell carcinoma was the predominant type of lung cancer among men but women were found to be more likely to have adenocarcinoma as compared to men and this was consistent with Kinnari S. Naik et al 3 and Kumar et al 7 The incidence of tuberculous inflammation was almost similar in the study of Pradeep Kumar Giri et al 4 (11.1%) and present study (20%).…”

Section: Discussionsupporting

confidence: 89%

“…The incidence rate of malignant lesions in the present study (63.41%) was similar to the study of Kinnari S. Naik et al 3 (75.6%) and Pradeep Kumar Giri et al 4 (75%). The incidence rate of inflammatory conditions was 6.10% in the present study as compared to 15.4% and 22.5% in the study of Kinnari S. Naik et al 3 In the present study, maximum malignant cases were seen in the age group of 61 to 70 years, which was similar to Anjan Das et al 5 study. The incidence rate was 25% in the age group of 51 to 60 years in the present study which almost similar to Pradeep Kumar Giri et al 4 study, which was 20%.…”

Section: Discussionsupporting

confidence: 84%

“…All the cases were positive for CK5/6 and p63 whereas negative for CK7 and TTF-1. These results showed concordance with Kinnari S. Naik et al, 3 Rekhtman et al 11 and Nicholson et al 12 A case of adenosquamous carcinoma was confirmed by using CK7, p63, and CK5/6. CK7 was positive in glandular areas whereas CK5/6 and p63 were positive in squamoid areas.…”

Section: Discussionsupporting

confidence: 84%

“…Present study and study by Pradeep Kumar Giri et al 4 , Kinnari S. Naik et al 3 and Deependra K Rai et al 6 showed similar result with predominance of adenocarcinoma followed by squamous cell carcinoma and small cell carcinoma. The incidence rate of adenocarcinoma (36.54%) and squamous cell carcinoma (30.77%) in the present study were almost similar to Kinnari S. Naik et al 3 study with the incidence rate of 38% and 22.4% respectively.…”

Section: Discussionsupporting

confidence: 80%

“…1 The overall lung cancer incidence rate is increased from 38.4 per 100,000 person-years during 1977 to 1981 to peak at 43.5 per 100,000 person-years during 1987 to 1991 and then decreased to 33.6 per 100,000 person-years during 2006 to 2010. 3 Lung cancer causes 36,000 deaths per year in UK, 25% of all cancer deaths, 8% of male deaths and 4% of female deaths and 49.9% cases in developing countries. 1,2 An increasing trend in cases of lung cancer is seen in India.…”

Section: B a C K G R O U N Dmentioning

confidence: 99%

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Histopathological Study of Lung Biopsy in Association with Immunohistochemistry

Lad¹,

Daveshwar²

2019

jemds

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A B S T R A C T BACKGROUNDLungs are the most exposed organs to different aggressions because of their anatomical and histological particularities. Lung lesions are common due to exposure to various risk factors. A few of them are pollution, smoking, human immunodeficiency virus (HIV), infections, tuberculosis, and malnutrition. An increasing trend in cases of lung cancer is being seen in India. Lung biopsy is a simple, relatively safe, rapid and reliable technique for the diagnosis of pulmonary mass lesions, particularly with the aid of computed tomography (CT) scan. We wanted to study the histopathological pattern of lung lesions along with its distribution with regard to age, sex, and site. METHODSThis is an observational study conducted at the RESULTS 82 cases were included in the study, out of which 52 cases (63.41%) were malignant, 5 cases (6.10%) were of inflammatory origin and 25 cases (30.49%) showed no evidence of malignancy. Male to Female ratio was 3:1. Most common age group was 51 to 60 years (31.71%). Most common histological type of malignancy was adenocarcinoma (36.54%), followed by squamous cell carcinoma (30.77%). CONCLUSIONSLung biopsy is reliable with high accuracy for diagnosis and subtyping of lung lesions. Immunohistochemistry is an important complimentary tool for routine diagnosis of lung cancers.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 84%