Shielded radiography with a laser-driven MeV-energy X-ray source

Chen, Shouyuan; Golovin, Grigory; Miller, C. A.; Haden, Daniel; Banerjee, Sudeep; Zhang, Ping; Liu, Cheng; Zhang, Jun; Zhao, Baozhen; Clarke, Shaun D.; Pozzi, Sara A.; Umstadter, Donald

doi:10.1016/j.nimb.2015.11.007

Cited by 15 publications

(6 citation statements)

References 24 publications

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“…An amplifier with enough channels to match each transducer element on the ring‐array is necessary to do this. Second, the fluence of the x‐ray tube can be increased with new x‐ray sources, such as the laser‐driven Thomson x‐ray source …”

Section: Medical Imagingmentioning

confidence: 99%

“…Second, the fluence of the x-ray tube can be increased with new x-ray sources, such as the laser-driven Thomson xray source. 88,89 It is believed that XACT imaging will find broad applications in both basic research and clinical care. Considering the use of XACT in breast imaging, minimal x-ray exposure can generate a 3D acoustic image of the breast, 90 which dramatically reduces the radiation dose to patients when compared to conventional breast CT.…”

Section: C Future Outlookmentioning

confidence: 99%

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Ionizing radiation‐induced acoustics for radiotherapy and diagnostic radiology applications

et al. 2018

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Acoustic waves are induced via the thermoacoustic effect in objects exposed to a pulsed beam of ionizing radiation. This phenomenon has interesting potential applications in both radiotherapy dosimetry and treatment guidance as well as low-dose radiological imaging. After initial work in the field in the 1980s and early 1990s, little research was done until 2013 when interest was rejuvenated, spurred on by technological advances in ultrasound transducers and the increasing complexity of radiotherapy delivery systems. Since then, many studies have been conducted and published applying ionizing radiation-induced acoustic principles into three primary research areas: Linear accelerator photon beam dosimetry, proton therapy range verification, and radiological imaging. This review article introduces the theoretical background behind ionizing radiation-induced acoustic waves, summarizes recent advances in the field, and provides an outlook on how the detection of ionizing radiationinduced acoustic waves can be used for relative and in vivo dosimetry in photon therapy, localization of the Bragg peak in proton therapy, and as a low-dose medical imaging modality. Future prospects and challenges for the clinical implementation of these techniques are discussed.

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Section: Medical Imagingmentioning

confidence: 99%

Section: C Future Outlookmentioning

confidence: 99%

Ionizing radiation‐induced acoustics for radiotherapy and diagnostic radiology applications

et al. 2018

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“…From figure 10, we can also see that the calculated data is very noisy. To evaluate the quality of the radiography images, the signal to noise ratio (SNR) is used [40], which is defined as SNR = ∆I/σ I , where ∆I is the change in the intensity caused by the target and σ I is the standard deviation of the background intensity. From the raw lineout, we can obtain that ∆I is about 2000 and σ I is about 250, therefore the SNR is about 8.…”

Section: Areal Density Analysesmentioning

confidence: 99%

Radiography of direct drive double shell targets with hard x-rays generated by a short pulse laser

Tian

Shan

et al. 2019

Nucl. Fusion

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Direct drive implosion experiments of a cone inserted double shell target were carried out at the SG-II Upgrade laser facility. Time-resolved radiographic images of the targets were obtained with hard x-rays generated by irradiating a short-pulse laser on a metal microwire embedded in a low-Z substrate. Since the SG-II Upgrade laser facility is mainly designed for indirect drive, it will lead to high direct illumination nonuniformity of the target surface. 2D nonuniformities of the inner shell were clearly shown by these images. Simple analytical estimations and radiation hydrodynamic simulations were also carried out, and calculations were consistent with the experimental results. Besides, areal density of the target was evaluated using the radiography images. Furthermore, it was found that the nanosecond laser had effects on hard x-ray generation, and the possibilities for improving the experimental results are discussed, which will be helpful to better understand the hydrodynamics of double shell or even triple shell target implosions.

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“…The x-ray and gamma ray sources based on LWFA (laser wake field acceleration) [1,2] have numerous potential practical applications in the nuclear field [2][3][4][5], such as medical isotope production [3,[6][7][8], nuclear waste transmutation [9][10][11][12], neutron and light elementary particlegeneration [13,14], and shielded radiography [15][16][17]. Many of these applications rely on the effect of photonuclear cross section enhancement in the vicinity of the giant dipole resonance (GDR) [5], which has a maximum from several MeV to a few tens of MeV.…”

Section: Introductionmentioning

confidence: 99%

Laser-based photonuclear production of medical isotopes and nuclear waste transmutation

Lobok¹,

Brantov²,

Bychenkov³

2022

Plasma Phys. Control. Fusion

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The results of complex simulations PIC-GEANT4 (particle-in-cell and Monte-Carlo) codes based on generation of a high-energy electron bunch by a short laser pulse propagating in relativistic self-trapping regime in a near-critical plasma has been applied to assess the possibility of medical isotope production and nuclear waste transmutation. It has been demonstrated that a 10Hz 30 fs 4J laser pulse is well suited for the production of therapeutic amounts of several standard medical radionuclides (111In, 123I, 103Pd, 62Cu, 64Cu). The use of direct electron irradiation has an advantage over the irradiation of Bremsstrahlung gamma radiation from the converter due to the simpliﬁcation of the production scheme without loss of radionuclide yield. The study of the transmutation of long-lived fusion products showed low eﬃciency and the need for preliminary isotopes separation. Achieving as little as 10% reduction in the activity of a 10 g sample requires continuous operation of the next generation laser system at a high repetition rate (1 MHz-100 kHz) for (1-10) years.

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Shielded radiography with a laser-driven MeV-energy X-ray source

Cited by 15 publications

References 24 publications

Ionizing radiation‐induced acoustics for radiotherapy and diagnostic radiology applications

Ionizing radiation‐induced acoustics for radiotherapy and diagnostic radiology applications

Radiography of direct drive double shell targets with hard x-rays generated by a short pulse laser

Laser-based photonuclear production of medical isotopes and nuclear waste transmutation

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