Shear Properties of Brain Tissue over a Frequency Range Relevant for Automotive Impact Situations: New Experimental Results

Nicolle, Stéphane; Mourad, Lounis; Willinger, Rémy

doi:10.4271/2004-22-0011

Cited by 99 publications

(138 citation statements)

References 33 publications

Supporting

Mentioning

128

Contrasting

Unclassified

Order By: Relevance

“…In 2004, Deck et al proposed a new 3D FEM, which describes in detail the complex geometry of the skull, including the evolution of the skull thickness throughout the skull and, for the first time, the reinforced beams which play an important role in its dynamical response to impact [21]. Concerning the brain mechanical properties, the authors improved two new laws based on original experimental tests by Nicolle et al, in 2003, focusing on high strain rates and non-linear behaviour in order to investigate the brain material properties' influence in the head model validation procedure against existing experimental brain deformation [22].…”

Section: Finite-element Modelsmentioning

confidence: 99%

Finite-element models of the human head and their applications in forensic practice

et al. 2008

Self Cite

View full text Add to dashboard Cite

Since the 1960s, predictive human head impact indices have been developed to help the investigation of causation of human head injury. Finite-element models (FEM) can provide interesting tools for the forensic scientists when various human head injury mechanisms need to be evaluated. Human head FEMs are mainly used for car crash evaluations and are not in common use in forensic science. Recent technological progress has resulted in creating more simple tools, which will certainly help to consider the use of FEM in routine forensic practice in the coming years. This paper reviews the main FEMs developed and focuses on the models which can be used as predictive tools. Their possible applications in forensic medicine are discussed.

show abstract

Section: Finite-element Modelsmentioning

confidence: 99%

Finite-element models of the human head and their applications in forensic practice

et al. 2008

Self Cite

View full text Add to dashboard Cite

show abstract

“…The deviatoric response of brain tissue was modeled using a linear viscoelastic (LVE) constitutive model based on experimental data of white matter tested in shear up to 6300 Hz. 34 Grey matter and the deeper nervous tissues materials were based on their relative stiffness to white matter: white matter was 50% stiffer than grey matter, 22 and the thalamus was 30% stiffer than white matter. 43 Since the regional variation of brain tissue relaxation was not significant, 43 the reduced relaxation function of each brain material remained the same.…”

Section: Head Modelmentioning

confidence: 99%

Development of a Finite Element Model for Blast Brain Injury and the Effects of CSF Cavitation

et al. 2012

View full text Add to dashboard Cite

Blast-related traumatic brain injury is the most prevalent injury for combat personnel seen in the current conflicts in Iraq and Afghanistan, yet as a research community,we still do not fully understand the detailed etiology and pathology of this injury. Finite element (FE) modeling is well suited for studying the mechanical response of the head and brain to blast loading. This paper details the development of a FE head and brain model for blast simulation by examining both the dilatational and deviatoric response of the brain as potential injury mechanisms. The levels of blast exposure simulated ranged from 50 to 1000 kPa peak incident overpressure and 1–8 ms in positive-phase duration, and were comparable to real-world blast events. The frontal portion of the brain had the highest pressures corresponding to the location of initial impact, and peak pressure attenuated by 40–60% as the wave propagated from the frontal to the occipital lobe. Predicted brain pressures were primarily dependent on the peak overpressure of the impinging blast wave, and the highest predicted brain pressures were 30%less than the reflected pressure at the surface of blast impact. Predicted shear strain was highest at the interface between the brain and the CSF. Strain magnitude was largely dependent on the impulse of the blast, and primarily caused by the radial coupling between the brain and deforming skull.The largest predicted strains were generally less than 10%,and occurred after the shock wave passed through the head.For blasts with high impulses, CSF cavitation had a large role in increasing strain levels in the cerebral cortex and periventricular tissues by decoupling the brain from the skull. Relating the results of this study with recent experimental blast testing suggest that a rate-dependent strain-based tissue injury mechanism is the source primary blast TBI.

show abstract

“…Brain tissue is generally considered anisotropic, but the significance of this anisotropy is still an open question. Some researchers have found considerable directional dependence of material properties [54], while others have found the opposite [55]. For the purpose of our study, we take brain tissue to be isotropic as it somewhat simplifies the constitutive model form and therefore reduces the number of model parameters that have to be estimated.…”

Section: (A) Experimental Datamentioning

confidence: 99%

A Bayesian approach to selecting hyperelastic constitutive models of soft tissue

Madireddy

Sista

Vemaganti

2015

Computer Methods in Applied Mechanics and Engineering

View full text Add to dashboard Cite

Shear Properties of Brain Tissue over a Frequency Range Relevant for Automotive Impact Situations: New Experimental Results

Cited by 99 publications

References 33 publications

Finite-element models of the human head and their applications in forensic practice

Finite-element models of the human head and their applications in forensic practice

Development of a Finite Element Model for Blast Brain Injury and the Effects of CSF Cavitation

A Bayesian approach to selecting hyperelastic constitutive models of soft tissue

Contact Info

Product

Resources

About