Shape controlled growth of gold nanoparticles by a solution synthesis

Chen, Ying; Gu, Xin; Nie, Chageng; Jiang, Zhiyuan; Xie, Zhaoxiong; Lin, Changjian

doi:10.1039/b504911c

Cited by 237 publications

(174 citation statements)

References 26 publications

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“…This is thought to be due to isotropic oscillations that are the same in all directions, as explained by the principle of SPR (16). The UV-Vis absorption spectra peaks of AuNPs did not change significantly for a storage period of at least 1 month signifying that the AuNPs were stable.…”

Section: Figmentioning

confidence: 93%

Cysteine‐capped gold nanoparticles suppress aggregation of proteins exposed to heat stress

et al. 2013

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Gold nanoparticles show a lot of promise as potential agents for drug delivery and disease diagnosis. Because of this, it is important that the interaction between gold nanoparticles and biomolecules be well characterized to avoid undesirable consequences. In this study, gold nanoparticles were synthesized by the reduction of gold salt by sodium borohydride in the presence of cysteine as the capping agent. The physical features of the nanoparticles were analyzed using Ultraviolet-Visible spectrophotometry and transmission electron microscopy. The interaction between gold nanoparticles and the following proteins: bovine serum albumin, citrate synthase, malate dehydrogenase, and human heat shock protein 70 was investigated by UV-Vis spectrophotometry. The stability of the proteins against heat stress was assessed by monitoring their aggregation at 48 8C, either in the presence or absence of gold nanoparticles. The gold nanoparticles were capable of suppressing the heat-induced aggregation of the proteins. Furthermore, apart from possessing independent protein-aggregation suppression function, the AuNPs also augmented the chaperone function of human heat shock protein 70. Findings from this study demonstrate that cyteinecoated gold nanoparticles exhibit chaperone-like activity and have the capability to stabilize proteins to which they may be conjugated. V C 2013 IUBMB Life, 65(5): 454-461, 2013.

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Section: Figmentioning

confidence: 93%

Cysteine‐capped gold nanoparticles suppress aggregation of proteins exposed to heat stress

et al. 2013

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“…It is noted that, although the highest peak in the XRD pattern is (111), the relative intensity of the (220) peak in the XRD pattern (Figure 1d) is significantly higher than those from decahedral Au particles with {111} facets [12] and from Au spherical particles. [13] The intensity of diffraction and the exposed surface of particles are two different aspects.…”

Section: Structure and Morphologymentioning

confidence: 97%

Facile Synthesis of (110)‐Plane‐Exposed Au Microflowers as High Sensitive Hydrogen Peroxide Sensors

Liu

Zhou

2015

Eur J Inorg Chem

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A flower‐like Au microstructure with a dominantly exposed active (110) plane has been prepared by a simple, facile method at room temperature. Various experimental factors that can control the shape of the Au microflowers have been investigated and optimized. Furthermore, the glassy carbon electrode modified with these Au microflowers exhibits high electrochemical activity towards H2O2 reduction. The sensor shows a linear range from 10 μM to 5.53 mM with a detection limit of 2 μM, which can be attributed to the exposed (110) planes and 3D hierarchical structure of the Au microflowers.

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“…These AuNPs can be dried and readily redispersed in solution without any aggregation making them outstanding precursors for further conjugation. [26] Furthermore purification of AuNPs stabilized with dodecanethiol from TOAB was reported by Schriffin.…”

Section: Chemical Methodsmentioning

confidence: 99%

“…[34] AuNPs can be manufactured into a variety of shapes including gold nanospheres, nanorods, nanobelts, nanocages, nanoprisms and nanostars. [26] Although gold may have fallen out of favor as a mainstream therapeutic agent, its use in nanoparticles is set to revive its application in medical care in both patient diagnosis and treatment. The …”

Section: Fig1 Gold Nanoparticle (Aunps)mentioning

confidence: 99%