Sexual transmission of arboviruses: More to explore?

Cardona-Ospina, Jaime A.; Alvarado-Arnez, Lucia Elena; Escalera-Antezana, Juan Pablo; Bandeira, António; Musso, Didier; Rodríguez‐Morales, Alfonso J.

doi:10.1016/j.ijid.2018.08.022

Cited by 8 publications

(6 citation statements)

References 6 publications

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“…In the case of leptospirosis, early diagnosis and treatment are related with shorter disease duration [17]. Moreover, some arboviral diseases may require long-term follow-up for assessment of chronic disease, like chikungunya [1,2], or may represent a risk for transmission through non-vectorial ways, like Zika [3]. Hence, etiologic diagnosis will improve not only management but will also provide information regarding the need of additional measures beyond the febrile disease.…”

Section: Discussionmentioning

confidence: 99%

“…The arrival of emerging arboviruses, such as chikungunya and Zika, in Latin America has extended the diagnostic spectrum of acute febrile patients. Although there is no specific management for Zika or chikungunya infections, the importance of etiologic diagnosis relies on the need for proper follow-up of those patients that evolve to chikungunya chronic disease [1,2], and in case of sexual transmission of transmission through body fluids in the case of Zika, and possibly other arboviruses [3]. The clinical picture is difficult to differentiate between arbovirus infections, and co-infections could be more frequent than expected [4,5].…”

Section: Introductionmentioning

confidence: 99%

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Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas

et al. 2018

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The febrile patient from tropical areas, in which emerging arboviruses are endemic, represents a diagnostic challenge, and potential co-infections with other pathogens (i.e., bacteria or parasites) are usually overlooked. We present a case of an elderly woman diagnosed with dengue, chikungunya and Leptospira interrogans co-infection. Study Design: Case report. An 87-year old woman from Colombia complained of upper abdominal pain, arthralgia, myalgia, hyporexia, malaise and intermittent fever accompanied with progressive jaundice. She had a medical history of chronic heart failure (Stage C, New York Heart Association, NYHA III), without documented cardiac murmurs, right bundle branch block, non-valvular atrial fibrillation, hypertension, and chronic venous disease. Her cardiac and pulmonary status quickly deteriorated after 24 h of her admission without electrocardiographic changes and she required ventilatory and vasopressor support. In the next hours the patient evolved to pulseless electrical activity and then she died. Dengue immunoglobulin M (IgM), non-structural protein 1 (NS1) enzyme-linked immunosorbent assay (ELISA), microagglutination test (MAT) for Leptospira interrogans and reverse transcription polymerase chain reaction (RT-PCR) for chikungunya, were positive. This case illustrates a multiple co-infection in a febrile patient from a tropical area of Latin America that evolved to death.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas

et al. 2018

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“…ZIKV sexual transmission has been suspected since 2008, when a traveler returning from an endemic area infected his partner who was in a region where vectors were absent [46]. Although potential sexual transmission of arboviruses other than ZIKV has been suspected, it has never been demonstrated [47]. ZIKV thus appears to be the only arbovirus that can be sexually transmitted [6].…”

Section: Sexual Transmission Of Zikv and The Effect Of Zikv Infection On Male Fertilitymentioning

confidence: 99%

Zika Virus

et al. 2020

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Zika virus (ZIKV), a neurotropic single-stranded RNA flavivirus, remains an important cause of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations where ZIKV has adapted to a nexus involving the Aedes mosquitoes and humans. To date, outbreaks of ZIKV have occurred in Africa, Southeast Asia, the Pacific islands, the Americas, and the Caribbean. Emerging evidence, however, suggests that the virus also has the potential to cause infections in Europe, where autochtonous transmission of the virus has been identified. This review focuses on evolving ZIKV epidemiology, modes of transmission and host-virus interactions. The clinical manifestations, diagnostic issues relating to cross-reactivity to the dengue flavivirus and concerns surrounding ZIKV infection in pregnancy are discussed. In the last section, current challenges in treatment and prevention are outlined.

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“…The arrival of emerging arboviruses, such as chikungunya and Zika, to Latin America has extended the diagnostic spectrum of acute febrile patients. Although there is not a specific management for Zika or chikungunya infection, the importance of etiologic diagnosis relies on the need of proper follow up of those patients that evolve to chikungunya chronic disease [1,2], and in the chance of sexual transmission of transmission through body fluids in the case of Zika, and possibly other arboviruses [3]. The clinical picture is difficult to differentiate between arboviruses infection, and co-infections could be more frequent than expected [4,5].…”

Section: Introductionmentioning

confidence: 99%

“…And in the case of leptospirosis, early diagnosis and treatment are related with shorter disease duration[17]. Moreover, some arboviral diseases may require long-term follow-up for assessment of chronic disease, like chikungunya[1,2], or may represent a risk for transmission through non-vectorial ways, like Zika[3]. Hence, etiologic diagnosis will improve not only management but also will provide information regarding the need of additional measures beyond the febrile disease.…”

mentioning

confidence: 99%

Fatal Dengue, Chikungunya and Leptospirosis Co-Infection: The Febrile Patient in Tropical Areas, Importance of Co-Infection Assessment

Cardona-Ospina¹,

Ce²,

Vásquez-Serna³

et al. 2018

Preprint

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Background: The febrile patient from tropical areas, in which emerging arboviruses are endemic, represent a diagnostic challenge and potential co-infections with other pathogens (i.e bacteria or parasites) are usually overlooked. Objectives: We present a case of an elderly woman diagnosed with dengue, chikungunya and Leptospira interrogans co-infection. Study Design: Case report. Results: An 87-year old woman from Colombia complained of upper abdominal pain, arthralgia, myalgia, hyporexia, malaise and intermittent fever accompanied with progressive jaundice. She had a medical history of chronic heart failure (Stage C, NYHA III), without documented cardiac murmurs, right bundle branch block, non-valvular atrial fibrillation, hypertension, and chronic venous disease. Her cardiac and pulmonary status quickly deteriorated after 24 hours of her admission without electrocardiographic changes and she required ventilatory and vasopressor support. In the next hours the patient evolved to pulseless electrical activity and then she died. Dengue IgM, NS1 ELISA, MAT for Leptospira interrogans and RT-PCR for chikungunya, were positive. Discussion: This case illustrates a multiple co-infection in a febrile patient from a tropical area of Latin America that evolved to death.

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Sexual transmission of arboviruses: More to explore?

Cited by 8 publications

References 6 publications

Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas

Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas

Zika Virus

Fatal Dengue, Chikungunya and Leptospirosis Co-Infection: The Febrile Patient in Tropical Areas, Importance of Co-Infection Assessment

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