Sexual precocity due to estrogen- and progesterone-producing organoid luteoma of the ovary

Seckel, H.; Plotz, E. J.

doi:10.1007/bf00438250

Cited by 13 publications

(2 citation statements)

References 41 publications

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“…Reviewers (Jolly, 1955;Seckel and Plotz, 1955;Wilkins, 1957;Eberlein et al, 1960) of the literature pertinent to sexual precocity and pseudoprecocity in infancy and childhood have been able to find only one report of a solid luteoma-like tumour as the cause (Seckel and Plotz, 1955). Even in this case the tumour was of a granulosa cell type with large areas of luteinization; however, the evidence for progesterone secretion and of luteinizing effects was good.…”

Section: Discussionmentioning

confidence: 95%

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Pseudoprecocity in an Infant due to a Luteoma of the Ovary

Campbell¹,

Danks²

1963

Archives of Disease in Childhood

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Section: Discussionmentioning

confidence: 95%

“…In 1957 Wilkins pointed out that the luteoma reported by Seckel and Plotz (1955) was the only ovarian tumour which had not been palpable at the time of presentation. These authors do not report any findings by palpation under anaesthesia, and the tumour was of the same size as that in our case.…”

Section: Discussionmentioning

confidence: 99%

Pseudoprecocity in an Infant due to a Luteoma of the Ovary

Campbell¹,

Danks²

1963

Archives of Disease in Childhood

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Granulosa-Cell Tumor of Ovary with Sexual Precocity

Steiner¹,

Hadawi²

1962

Arch Pediatr Adolesc Med

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Granulosa-Theca-Cell Tumor of the Ovary in Children

Zangeneh¹

1968

Arch Pediatr Adolesc Med

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WITHIN RECENT years granulosa\x=req-\ theca-cell tumors have attracted much interest, primarily because of their hormonal function. These tumors are the principal feminizing neoplasms of the ovary; and it has been emphasized that when they occur in prepubertal females, they almost always cause sexual precocity. Because of this known and rather constant relationship, the diagnosis of granulosa-theca-cell tumor usually is entertained in the differential diagnosis of isosexual precocity in females. Although it is appropriate that some consideration should be given to this diagnosis in all such patients, it should be remembered that not more than 10% of cases of sexual precocity in the female arise from ovarian tumors.The purpose of this article is to review the literature on this interesting problem, especially as it relates to children, and to emphasize the pitfalls in making the diagnosis. IncidenceThe rarity of granulosa-theca-cell tumors of the ovary is appreciated if it is remembered that primary ovarian tumors are rare, and that of these the granulosatheca-cell variety constitute only about

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Sexual precocity due to estrogen- and progesterone-producing organoid luteoma of the ovary

Cited by 13 publications

References 41 publications

Pseudoprecocity in an Infant due to a Luteoma of the Ovary

Pseudoprecocity in an Infant due to a Luteoma of the Ovary

Granulosa-Cell Tumor of Ovary with Sexual Precocity

Granulosa-Theca-Cell Tumor of the Ovary in Children

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