Sexual Dysfunction in Women with ESRD Requiring Hemodialysis

Strippoli, Giovanni F.M.; Depression, Collaborative

doi:10.2215/cjn.12601211

Cited by 92 publications

(56 citation statements)

References 44 publications

(48 reference statements)

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“…Sexual dysfunction also contributes to low pregnancy rates in women on dialysis. Among women on hemodialysis, 84% reported sexual dysfunction and only 35% of women reported being sexually active [6]. Depressive symptoms, medications, anemia and negative body image (potentially related to the presence of catheters and fistulas) contribute to low libido [7].…”

Section: Fertility and Esrdmentioning

confidence: 99%

Pregnancy and End-Stage Renal Disease

2018

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Pregnancy is uncommon in women with end-stage renal disease (ESRD). Fertility rates are low in women on dialysis, and physicians still frequently counsel women with ESRD against pregnancy. Advancements in the delivery of dialysis and obstetric care have led to improved live birth rates in women on dialysis, so pregnancy for young women with ESRD is now more feasible and safer. However, these pregnancies remain high-risk for both maternal and fetal complications, necessitating experienced multidisciplinary care. In this article, we review fertility issues in women with ESRD, discuss pregnancy outcomes in women on dialysis, and provide an approach for management of pregnant women with ESRD.

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Section: Fertility and Esrdmentioning

confidence: 99%

Pregnancy and End-Stage Renal Disease

2018

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“…The association of increasing age with sexual dysfunction has been previously demonstrated in nonuremic subjects [23]. Strippoli's study showed that the prevalence of sexual dysfunction increased by 8% per 1-year increase [11]. Basok's study showed that low sexual function had relationship with existing diabetes [12].…”

Section: Discussionmentioning

confidence: 89%

“…In Seethala's study, 80% of women undergoing hemodialysis had a score of sexual function index less than 26.55 (7). More recently, in a large multicentric cross-sectional study, Strippoli et al [11] reported that 84% of women on maintenance hemodialysis had sexual dysfunction based on a cut-point of 26.55. The prevalence of sexual dysfunction in women who are of an age similar to that of our cohort and who have normal kidney function remains incompletely investigated.…”

Section: Discussionmentioning

confidence: 95%

Sexual Function and Correlates in Women Undergoing Maintenance Hemodialysis in Cameroon: A Multi-centric Study

Teuwafeu¹,

Ashuntantang²,

Essi³

et al. 2016

TOUNJ

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Purpose of The Study:The aim of this study was to describe sexual function disorders and investigate associated factors in women on maintenance hemodialysis in Cameroon. Methods:This was a cross-sectional study of three months duration (August-October 2014) in adult women on maintenance hemodialysis (HD) at three HD facilities in Cameroon. Patients with active psychiatric disease, infection or uncontrolled congestive heart failure were excluded. We use the Rosen questionnaire for evaluating female sexual function (FSFI), the Beck depression Inventory (BDI) and the short form (SF-36) of WHOQOL-BREF questionnaire to evaluate the quality of life (QOL). Logistic regressions were used to investigate the predictors of sexual function disorders. Results:We included 52 women with the mean age of 38±13 years (min-max: 18-69), with 31 (62%) being of child-bearing age (18-44 years). All participants had at least one sexual function abnormality including sexual dysfunction (75%), abnormalities of the menstrual cycle (83%), and sexual inactivity (30%). In women of child-bearing age, reported menstrual disorders were: irregular menses (45%), non-gravid amenorrhea (40%), oligo-menorrhea (25%), poly-menorrhea (25%), metrorrhagia (6%), and menorrhagia (3%). Ten of the 31 women had more than one menstrual disorder. Sexual dysfunction included: decreased sexual desire (56%), decreased sexual arousal (39%), decreased vaginal lubrication (49%), and failure to achieve orgasm (46%), sexual dissatisfaction (51%), and dyspareunia (36%). Advanced age (p = 0.0046), depression (p<0.0001), anemia (p=0.0005) and poor quality of life were negatively associated with sexual dysfunction. Sexual inactivity (p = 0.035) was equally associated with poor quality of life. Conclusion:Our results suggest that disorders of sexual function are common in women on maintenance hemodialysis, and are associated with depression, poor quality of life, advanced age, and anemia.

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“…However, all dialysis patients are associated with obvious severe somatic complications. If such conditions including sexual dysfunction 25,26) affect emotional disturbance, the SDS score may rather reflect the patient's true emotional condition. Note that the association between emotional disturbance assessed by the SDS test and mortality was extremely strong.…”

Section: Discussionmentioning

confidence: 99%

Emotional disturbance assessed by the Self-Rating Depression Scale test is associated with mortality among Japanese Hemodialysis patients

Kazama

Wakasugi

et al. 2018

FJMS

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Emotional disturbance including depression is associated with increased mortality among dialysis patients. The Self -Rating Depression Scale (SDS) is a simple tool for assessing emotional disturbance. This study investigated the relationship between emotional conditions as assessed with the SDS test and mortality among 491 hemodialysis patients. At baseline, 183 (37.3%), 180 (36.7%), 108 (22.0%), and 20 (4.1%) were classified as normal, borderline depression, depression, and severe depression, respectively. During the two years of observation period, 57 of 491 (11.6%) died. The SDS scores in the non -survivors were significantly higher than those in the survivors (p<0.0001). Logistic analyses showed that the diagnoses made by the SDS test were associated with significantly greater risks for all -cause mortality (99%CI : 1.905 -3.698 for that without adjustment, 1.999 -4.382 for that with full adjustment). When the SDS score = 50 was selected as the cut off value, the test screened two -year all cause death with sensitivity = 57.9% and the specificity = 78.1%. In conclusion, hemodialysis patients had high prevalence of emotional disturbance assessed by the SDS test, and high SDS score was significantly associated with all -cause mortality. These findings underscore the importance of screening for emotional conditions using the SDS test among hemodialysis patients.

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Sexual Dysfunction in Women with ESRD Requiring Hemodialysis

Cited by 92 publications

References 44 publications

Pregnancy and End-Stage Renal Disease

Pregnancy and End-Stage Renal Disease

Sexual Function and Correlates in Women Undergoing Maintenance Hemodialysis in Cameroon: A Multi-centric Study

Emotional disturbance assessed by the Self-Rating Depression Scale test is associated with mortality among Japanese Hemodialysis patients

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