Sexual dysfunction in patients with psoriasis

Abstract

Psoriasis can have a significant impact upon sexual function. The aim of this study was to investigate sexual function in females and males with psoriasis and to evaluate whether coexistent depression has an additional negative effect on sexual function in these patients. A total of 66 female subjects (39 with psoriasis and 27 healthy volunteers as a control group) and 70 male subjects (39 with psoriasis and 31 healthy volunteers as a control group) were enrolled in the study. A Psoriasis Area and Severity Index (PASI) was used to determine the severity of psoriasis for the patient groups. The Female Sexual Function Index (FSFI) was used to assess female sexual function and the International Index of Erectile Function (IIEF) was used to evaluate male sexual function. Quality of life was assessed with the Dermatology Life Quality Index (DLQI). The diagnosis of depression was made according to the Structured Clinical Interview for DSM-IV (SCID-I) interview and Hamilton Depression Rate Scale (HDRS) was used for grading depression. FSFI total score was found to be significantly decreased in female psoriatic patients without depression and psoriatic patients plus depression compared with healthy controls (24.09 +/- 5.33 vs. 24.25 +/- 4.52 vs. 28.12 +/- 3.48, respectively, p = 0.004). However, FSFI score was not significantly different between patients with psoriasis without depression and those with psoriasis plus depression (p > 0.05). IIEF total score was also found to be significantly decreased in male psoriasis without depression and psoriasis plus depression patients compared with healthy controls (54.21 +/- 13.07 vs. 52.0 +/- 14.73 vs. 61.69 +/- 9.49, respectively, p = 0.023). The difference in IIEF scores between patients with psoriasis without depression and in those with psoriasis plus depression were not statistically significant (p > 0.05). The results of the study demonstrated that patients with psoriasis, especially females have distinct sexual dysfunction compared with healthy controls, and coexistent depression has no additional negative effect on sexual dysfunction in our patients. Patients with psoriasis should be evaluated in terms of sexual function in order to provide a better quality of life.

Profound disturbances of sexual health in patients with acne inversa

“…3 Moreover, in the current study, women with AI reported age at disease onset approximately 6 years younger compared with male patients, which DLQI, mean 6 SD (range) 14.4 6 6.6 (1-26) 9.6 6 6.9 .03* FKKS SSEX, mean 6 SD (range) 19.5 6 5.1 (12-32) 23.5 6 5.8 (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32) .02* Sartorius score, mean 6 SD (range) 52.9 6 35.5 (7-138) 52. 8 6 27.3 (17-114) .72…”

“…Examples are psoriasis vulgaris, [16][17][18] atopic dermatitis, 13 chronic hand eczema, 19 vitiligo, and chronic urticaria. 20 To our knowledge, the degree of sexual dysfunction in patients with AI is unknown, until today.…”

Prevalence and Associated Factors of Erectile Dysfunction in Patients With Moderate to Severe Psoriasis and Healthy Population: A Comparative Study Considering Physical and Psychological Factors

“…On the other hand, anxiety and depression, two of the main psychological comorbidities of psoriasis patients and also linked to ED, have seldom been assessed in these studies. Only one study has attempted to take into account the influence of depression on sexual function in people with psoriasis (Turel Ermertcan et al, 2006), although the authors did not concurrently assess anxiety, other physical comorbidities, or health habits. Thus, no study to date has considered the importance of anxiety in the relationship betweenpsoriasisandED (Table 1).Anxietyanddepressioncould be intermediatefactors betweenpsoriasisand ED,as they are more frequent among patient with psoriasis and are associated with ED.…”

Secukinumab demonstrates greater sustained improvements in daily activities and personal relationships than ustekinumab in patients with moderate‐to‐severe plaque psoriasis: 52‐week results from the CLEAR study

“…clothes may stick to open areas and traumatize lesions),7 which can lead to further impairment in HRQOL. Psoriasis also impacts emotional and sexual functioning, which disrupts social interactions and intimate relationships 8, 9, 10, 11, 12, 13, 14. Sensitive issues, however, such as sexual relationships, typically are not assessed by clinicians 12.…”