Prevalence and Associated Factors of Erectile Dysfunction in Patients With Moderate to Severe Psoriasis and Healthy Population: A Comparative Study Considering Physical and Psychological Factors

Molina‐Leyva, Alejandro; Molina-Leyva, Ignacio; Almódovar-Real, Ana; Ruiz‐Carrascosa, J.C.; Naranjo‐Sintes, Ramón; Jiménez-Moleón, José-Juan

doi:10.1007/s10508-016-0757-8

Cited by 19 publications

(13 citation statements)

References 43 publications

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“…Several epidemiological studies have investigated the relationship between psoriasis and depression or SIB (Table 1). 11,[26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] Because of differences in study design, notably in patient populations and measurement methods (e.g. self-reported, diagnostic codes), reported rates of psychiatric comorbidities vary.…”

Section: Mental Health Disorders In Patients With Psoriasismentioning

confidence: 99%

“…Patients with severe psoriasis had significantly higher scores on the Carroll rating scale for depression (CRSD), a 52‐item patient‐reported instrument used to screen for depressive symptoms, than patients with less‐severe psoriasis (CRSD, 13.4 vs. 8.6; P < 0.001), and 7.2% of those with severe psoriasis had active suicidal ideations. Several epidemiological studies have investigated the relationship between psoriasis and depression or SIB (Table ) . Because of differences in study design, notably in patient populations and measurement methods (e.g.…”

Section: Mental Health Disorders In Patients With Psoriasismentioning

confidence: 99%

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Depression and suicidality in psoriasis: review of the literature including the cytokine theory of depression

Koo

Marangell

Nakamura

et al. 2017

Acad Dermatol Venereol

167

152

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Psoriasis can be a socially isolating disease due to debilitating physical symptoms and the stigma patients feel because of the appearance of their skin. Mental health comorbidities such as anxiety, depression and suicidal ideation and behaviour (SIB) are prevalent in patients with psoriasis. Patients with mild psoriasis can experience psychiatric comorbidities; however, disorders such as depression and SIB are more common in patients with severe psoriasis or psoriatic arthritis. Psychiatric disorders can both result from and contribute to progression of psoriasis, suggesting that psoriasis and psychiatric conditions, such as depression, may have overlapping biological mechanisms. Proinflammatory cytokines such as interleukin (IL)-1 and IL-6 are elevated in both psoriasis and depression, indicating that the inflammatory process may be involved in the progression of both diseases. Elevated cytokine levels in the central nervous system cause physiologic and biochemical changes that may contribute to the development of depression. In this review of the literature, we discuss the evidence that supports the association of psoriasis with mental health disorders and the tools used to detect the presence of these comorbidities. Additionally, we review the most prominent hypotheses on the mechanisms by which the inflammatory response and elevated cytokines can cause depression. These results highlight the role that systemic inflammation plays in the various mental health comorbidities associated with psoriasis, including depression and SIB.

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Section: Mental Health Disorders In Patients With Psoriasismentioning

confidence: 99%

Section: Mental Health Disorders In Patients With Psoriasismentioning

confidence: 99%

Depression and suicidality in psoriasis: review of the literature including the cytokine theory of depression

Koo

Marangell

Nakamura

et al. 2017

Acad Dermatol Venereol

167

152

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“…With regard to demographic facets, the key factors reported were sex, 13, 28–38 age, 31, 35, 38–41 education level, 34, 36, 41–43 ethnicity, 32, 42 BMI, 44, 45 sleep quality, 46, 47 marital status, 28, 48 exercise amount, 49 family history, 43 the use of topical treatment only, 32 personality 13 and history of smoking. 44 Females were more prone to depressive and psychosocial maladaptation than males with skin disease. 28, 31, 50 Because females were more likely to believe in the importance of physical appearance to their personal or social values than males, their investment in physical attractiveness was significantly increased.…”

Section: Resultsmentioning

confidence: 99%

“…With respect to psychological facet, the related factors included anxiety and depression, 36, 39, 40, 42, 44–46, 48, 55, 60, 61, 65 self-esteem, 13, 34, 53, 66 body image, 30, 53, 67 stigma 29, 41 and suicidal ideation. 46, 48 Skin disease patients have a high level of anxiety or depression.…”

Section: Resultsmentioning

confidence: 99%

The psychosocial adaptation of patients with skin disease: a scoping review

et al. 2019

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BackgroundSkin disease is a global public health problem that often has physiological, psychological and social impacts. However, it is not very clear how to adapt to these impacts, especially psychosocial adaptation of patients with skin disease.MethodsWe searched EMBASE, PubMed, CINAHL and PsycINFO from 2009 to 2018. The following themes were extracted from the included articles: the concepts, related factors, and interventions for psychosocial adaptation of patients with skin disease. Two reviewers independently screened and analyzed.ResultsFrom 2261 initial records, 69 studies were identified and analyzed. The concept of psychosocial adaptation in patients with skin disease was referred to under an assortment of descriptions. The related factors for psychosocial adaptation in patients with skin disease included the following: demographic factors (sex, age, education level, ethnicity, BMI, sleep quality, marital status, exercise amount, family history, the use of topical treatment only, personality and history of smoking); disease-related factors (disease severity, clinical symptoms, localization and duration); psychological factors (anxiety/depression, self-esteem, body image, stigma and suicidal ideation); and social factors (social support, social interaction, sexual life, economic burden and social acceptance). Despite being limited in quantity, several studies have clarified the benefits of adjuvant care in the form of cognitive behavioral training, educational training and self-help programs, all of which have become common methods for dealing with the psychosocial impacts.ConclusionsBased on the previous literatures, we constructed a protocol of care model for psychosocial adaptation in patients with skin disease. It not only provided the direction for developing new instruments that could assess psychosocial adaptation statue, but also a basis for helping patients adjust to changes in skin disease.

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“…34 Of note, patients with mild psoriasis seem to be predisposed to more severe ED, 35 and depression seems to be a significant contributor to ED in psoriasis. 36,37 Psoriasis and Vascular Damage: The Common Pathways and Markers of Vascular Disease…”

mentioning

confidence: 99%