Background: Variations in Morphological study of Maxillary sinus (MS) has anatomical, medico-legal and ethnic importance. Hence adult MS of both Sexes were studied radiologically (CT) Method: 20 Male and 20 female adults aged between 20-50 years were studied with CT images to measure the mediolateral, Supero-inferior and antero posterior dimensions and the volume of Maxillary sinus in both genders and obtained results were studied and compared statistically. Results: The mean value MLR in Males was 28.62 (S0±3.24) females 26.10 (±5.60), t test was 1.74 and P<0.01. The mean value of SIR was 39.11 (±4.66) in males, 34.20 (±5.43) in females t test 3.06 P<0.01. Mean value of APR in males 43.58 (±2.69) and females 37.02 (±3.03) t test-7.24 P<0.01. Mean value of MLL in males was 28.02 (±4.03), females 24.11 (±5.17) t test 2.66 and P<0.01. Mean values SIL in males was 37.82 (3.32), females 34.12 (±5.60) t test. 2.54, P<0.01. Mean value of APL males was 41.78 (1.62) females 38.10(±1.98) t test was 6.43 and P<0.01. Mean values volume of right MS in Male 17.52 (±3.52) female 12.60 (± 4.14) t test 4.04, P<0.01. Mean value of left volume of MS in Males was 16.18 (±2.84), females 11.84 (± 3.88) t test was 4.03 P<0.01. Conclusion: This significant findings between Male and female MS has anatomical, anthropological and medico-legal importance in the adults. Key Word: MS Maxillary sinus CT = Computerised Tomography, VR=volume of right MS, VL=volume of left MS.