Sexual dimorphism in Odontobutis sinensis brain-pituitary-gonad axis and liver highlighted by histological and transcriptomic approach

Zhou, Lingling; Yang, Rui-Bin; Tian, Hua; Qin, Xiangfeng; Cheng, Ya; Shi, Xuetao; Xia, Chuanhui; Cai, Tianyi; Xie, Yunyi; Jia, Yongyi; Hu, Guangfu

doi:10.1016/j.gene.2022.146264

Cited by 4 publications

(1 citation statement)

References 34 publications

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“…Some studies have indicated that the phenotypes of sexual dimorphism in invertebrates are the consequences of sex-biased gene expression and are controlled by multiple critical genes during growth and development [29]. Te growth, reproduction, and metabolism of fsh mainly depend on the somatotropic axis (brain-pituitary-liver) and reproductive axis (brain-pituitary-gonad) [30]. Comparative transcriptome analysis revealed many diferentially expressed genes (DEGs) in the hypothalamus and pituitary of Mystus wyckioides between males and females, and most of these DEGs were involved in gonad development and growth [31].…”

Section: Introductionmentioning

confidence: 99%

Growth Patterns and Growth-Axis Gene Expressions in Sexual Dimorphism of Silurus asotus Linnaeus, 1758

Qiao

et al. 2023

Journal of Applied Ichthyology

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Aquaculture has tremendous economic significance in distinguishing males and females in the juvenile Silurus asotus (Linnaeus, 1758) to obtain a female population with tremendous growth potential. To investigate the potential biological markers between young males and females S. asotus, we analyzed the characteristics of sexual dimorphism by measuring the 14 length traits and 9 weight indicators in an artificial insemination population at 3, 5, and 7 months. In addition, quantitative real-time PCR (qRT-PCR) was performed to determine the sexually dimorphic expression of the growth hormone-1 gene (GH-1), growth hormone receptor gene (GHR), and insulin-like growth factor gene (IGF-1) in the hypothalamus, pituitary, gonad, and liver, at 3, 5, and 7 months. The results showed that in morphology, except for eye diameter and the distance between the pelvic and anal fins in 3-month fish, all other morphological indicators were significantly ( P < 0.05 ) or very significantly ( P < 0.01 ) different between juvenile males and females. The visceral weight, eviscerated weight, and intestine weight in females were significantly ( P < 0.05 ) or very significantly ( P < 0.01 ) higher than in males at 5 and 7 months. Joint static allometric analyses on 14 length indicators relative to weight showed different sex growth patterns in 3-month, 5-month, and 7-month fish. In gene expression patterns, GH-1, IGF-1, and GHR were highly expressed in the pituitary, with higher levels in females ( P < 0.05 or P < 0.01 ). In contrast, the three genes were all more highly expressed in the testis than in the ovary ( P < 0.01 ), indicating their essential roles in testis development. Our results demonstrate that S. asotus has female-biased sexual dimorphism. The length traits related to head shapes could be the potential phenotype marker to distinguish females and males in 7-month juveniles.

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Section: Introductionmentioning

confidence: 99%

Growth Patterns and Growth-Axis Gene Expressions in Sexual Dimorphism of Silurus asotus Linnaeus, 1758

Qiao

et al. 2023

Journal of Applied Ichthyology

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Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice

Zhang

Retyunskiy

Qiao

et al. 2022

Sci Rep

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Alloferon-1 have been proposed as an effective peptide to enhance antitumoral immunity, antiviral defense and anti-inflammatory activity. This work aimed to assess anti-inflammatory effects of alloferon-1 against acute inflammation and histopathological deformations in λ-carrageenan-induced paw edema in mice. Systemic pretreatment with alloferon-1 (22.0 mg/kg) intraperitoneally injected mice showed a significant reduction in paw thickness and vascular permeability. Alloferon-1 prevented λ-carrageenan-evoked exudation and the neutrophil influx to the mouse pleura and the neutrophil migration into carrageenan-stimulated mouse air pouches based on the histopathological changes in the paw tissues. Administration of alloferon-1 also suppressed the expression of the inflammatory cytokines in the inflamed paw tissues such as tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein 1 (MCP1), interleukin-5 (IL-5), etc. detected by Luminex liquid chip. Collectively, the present study provides evidences for the marked anti-inflammatory effects of alloferon-1 which might represent new therapeutic options for the treatment of acute inflammatory diseases.

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Annual reproductive cycle of Chinese sleeper Perccottus glenii , Dybowski, 1877 (Teleostei: Gobiiformes: Odontobutidae) an invasive fish inhabiting Central Europe

Kirczuk,

Dziewulska,

Czerniejewski

et al. 2024

The European Zoological Journal

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Sexual dimorphism in Odontobutis sinensis brain-pituitary-gonad axis and liver highlighted by histological and transcriptomic approach

Cited by 4 publications

References 34 publications

Growth Patterns and Growth-Axis Gene Expressions in Sexual Dimorphism of Silurus asotus Linnaeus, 1758

Growth Patterns and Growth-Axis Gene Expressions in Sexual Dimorphism of Silurus asotus Linnaeus, 1758

Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice

Annual reproductive cycle of Chinese sleeper Perccottus glenii , Dybowski, 1877 (Teleostei: Gobiiformes: Odontobutidae) an invasive fish inhabiting Central Europe

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