1999
DOI: 10.1538/expanim.48.37
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Sex Differences in Susceptibility of ICR Mice to Oral Infection with Corynebacterium kutscheri.

Abstract: Sex difference in susceptibility to oral infection with Corynebacterium (C.) kutscheri was experimentally studied in ICR mice. Immature (4-week-old) and adult (14-week-old) mice were inoculated with two infecting doses of C. kutscheri, and necropsied for bacteriological and serological survey 4 weeks after the bacterial infection. No macroscopic lesions at necropsy were demonstrated, except for one adult male given 10(9) bacteria. In immature mice, C. Kutscheri isolated from the oral cavity and cecum with FNC … Show more

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Cited by 12 publications
(4 citation statements)
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“…We have also found differences in susceptibility to infection with C. kutscheri among sexes and various mouse strains (Amao et al 1993, Komukai et al 1999. These differences may be important when screening for infection with C. kutscheri.…”
Section: Discussionsupporting
confidence: 51%
“…We have also found differences in susceptibility to infection with C. kutscheri among sexes and various mouse strains (Amao et al 1993, Komukai et al 1999. These differences may be important when screening for infection with C. kutscheri.…”
Section: Discussionsupporting
confidence: 51%
“…Sex differences in the integument microbiota of adults have been shown in various species spanning multiple taxonomic groups, including humans (Fierer et al 2008), greater sac-winged bats, Saccopteryx bilineata (Voigt et al 2005), white-tailed deer, Odocoileus virginianus (Alexy et al 2003), and great tits, Parus major (Saag et al 2011). As is typical of vertebrate reproductive development, sexual maturity in meerkats is associated with sex-specific hormonal changes (Moss et al 2001) that might directly affect microbiota (Styrt and Sugarman 1991;Komukai et al 1999;Freestone et al 2008) or the microenvironment in which they flourish.…”
Section: Discussionmentioning
confidence: 99%
“…Females mount more vigorous antibody-and cellmediated immune responses than males following infection or vaccination. [1][2][3][4][5] However, increased immunity in females is a double-edged sword: its beneficial effects against infectious diseases are countered by the greater possibility of autoimmune diseases. [6][7][8] Furthermore, in order to be compatible with reproduction, immune responses against allogeneic sperm or the semi-allogeneic zygote must be prevented.…”
Section: Introductionmentioning
confidence: 99%