The effect of weft density, weft yarn count and waterproof and oilproof finishing on the seam slippage properties were investigated for a range of fabrics for tailored garments. It was shown that the increase of the weft density positively affects the seam slippage performance, while the effects depend on the magnitude of increasing the weft density and a testing direction. The introduction of a higher weft yarn count results in the improved warp slippage performance. As a result of the higher weft yarn count, the seam opening decreased for 40% for warp slippage. The fabrics having waterproof and oilproof finishing showed worsened seam slippage properties. The analysis of variance confirmed that weft density, weft yarn count and waterproof and oilproof finishing are statistically significant factors on the seam opening as a result of the yarn slippage of yarns at seams.