Severity of whooping cough in England before and after the decline in pertussis immunisation.

Pollock, T.M.; Miller, Elizabeth; Lobb, J

doi:10.1136/adc.59.2.162

Cited by 26 publications

(19 citation statements)

References 4 publications

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“…As about two thirds of infants with pertussis are admitted to hospital, factors that seem to be associated with an increased risk of pertussis may in fact be associated with an increased risk of hospital admission. 1 2 The admission rate for pertussis in New Zealand is five to 10 times higher than in England and Wales and the United States 3. We determined whether immunisation reduced the risk of admission to hospital for pertussis by comparing infants admitted with pertussis and infants admitted with other acute respiratory illnesses.…”

mentioning

confidence: 99%

Delayed immunisation and risk of pertussis in infants: unmatched case-control study

Grant

Roberts²,

Scragg³

et al. 2003

BMJ

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mentioning

confidence: 99%

Delayed immunisation and risk of pertussis in infants: unmatched case-control study

Grant

Roberts²,

Scragg³

et al. 2003

BMJ

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“…Thus, although these data were collected during the 1990s, they remain applicable to current inpatient management. [20][21][22][23][24] Our study was limited to a case series from one city during one epidemic, and our findings are derived from a retrospective analysis of clinical data. These initial observations require confirmation in prospective studies of other populations.…”

Section: Discussionmentioning

confidence: 99%

When to Discharge Children Hospitalized With Pertussis?

Lurie¹,

Reed²

2009

Academic Pediatrics

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“…After the vaccine came into widespread use, infants <1 year of age of age have remained the most susceptible to pertussis morbidity, [99][100][101] while in the pre-vaccine era the pertussis rate was highest among children aged between 1 and 5 years. This age group still accounts for the highest number of reported pertussis cases in some countries including Italy, Sweden and the former West Germany, where immunization is limited.…”

Section: Populations Susceptible To Pertussismentioning

confidence: 99%

Which Strategy for Pertussis Vaccination Today?

Girard

2002

Pediatric Drugs

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Pertussis (whooping cough) remains an epidemic disease responsible for infant and child morbidity and mortality, and is perceived as a serious public health problem. Since the widespread use of whole-cell pertussis vaccines in the 1940s, vaccination programs have varied greatly between countries. National specificity is a function of several factors. The most important are: vaccine efficacy and tolerability;vaccine coverage and distribution; and vaccine acceptance by parents and professionals. During the 1970s, Sweden, England, Wales and Japan provided contrasting examples of the attitude of health authorities to the use of whole-cell vaccines. The increase in pertussis incidence was noted as a consequence of active opposition to this vaccine. The re-emergence of pertussis in the 1990s, in countries with high vaccination coverage and increased incidence of disease in individuals >15 years and <6 months of age, has drawn attention to the role of booster doses of pertussis vaccines and their introduction into regular vaccination programs. The use of acellular vaccines for booster doses for adolescents and adults would seem unambiguous because of their decreased reactogenicity, although the exact schedule has yet to be established. The choice between the two kinds of vaccines is more difficult for primary courses, where safety and efficacy profiles are similar, and the attitude towards acellular vaccines varies from country to country. In this case, the strategy adopted results from the national history of pertussis infection and from the quality of the available whole-cell vaccine. Two contrasting examples are the US, where acellular vaccines were licensed for the primary series in the 1990s, and the UK, where whole-cell vaccines are exclusively used for primary immunization. The changing epidemiology of pertussis, and its local diversification, would suggest that at present it is difficult to define a single worldwide strategy with only one kind of vaccine and one schedule. In order to control pertussis incidence, each country should continue to determine the best national vaccination program established in very close relation to the past and present epidemiological situation and available healthcare resources.

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Severity of whooping cough in England before and after the decline in pertussis immunisation.

Cited by 26 publications

References 4 publications

Delayed immunisation and risk of pertussis in infants: unmatched case-control study

Delayed immunisation and risk of pertussis in infants: unmatched case-control study

When to Discharge Children Hospitalized With Pertussis?

Which Strategy for Pertussis Vaccination Today?

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