Severity assessment of acute pancreatitis: applying Marshall scoring system

Carioca, André Lanza; Jozala, Débora Rodrigues; de, Lucas Oliveira; Rodrigues, José Mauro da Silva

doi:10.1590/0100-69912015005010

Cited by 10 publications

(10 citation statements)

References 21 publications

(21 reference statements)

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“…Patients with MAP did not experience these complications. BISAP, modified Balthazar CT, Ranson, APACHE II and Marshall scores6 were calculated at baseline according to our clinical practice. The HCT, WCC, neutrophil count (NC), lymphocyte count (LC), LR and NLR were analyzed.…”

Section: Methodsmentioning

confidence: 99%

“…It has been stated that scoring systems such as BISAP, Balthazar CT, Ranson, and APACHE II, which usually combine symptoms and laboratory results to evaluate the patient’s condition, can be used to determine the severity of AP. However, they still need to be improved and perfected because of their complexity and low sensitivity67. Therefore, there is an urgent need for a fast, simple, and sensitive method to stratify patients at the time of admission or shortly thereafter.…”

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confidence: 99%

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A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis

Yang

Huang

et al. 2017

Sci Rep

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The early diagnosis and severity grading for acute pancreatitis (AP) are difficult to determine because of the complexity and differences in disease process. To date, few studies have investigated the role of lymphocyte ratio (LR) in AP. Therefore, the objective of the present study was to investigate the prognostic value of LR as an indicator in AP, as well as determine an optimal cut-off value for the severity prediction. There were two hundred four patients involved in this study, ninety-two of whom had severe acute pancreatitis (SAP). The LR was analyzed on admission and correlated with severity, which was determined using the Atlanta classification. The optimal cut-off value for LR was generated using receiving operator characteristic (ROC) curves. The results showed that the LR in the SAP group decreased significantly compared to the mild acute pancreatitis (MAP) group (8.82 vs. 13.43). The optimal cut-off value obtained from ROC curves was 0.081, with a sensitivity of 80.4%, a specificity of 53.3%, a positive likelihood ratio of 1.722, and a negative likelihood ratio of 0.368. In conclusion, the LR is obviously related to the condition of AP patients and is valuable for the differential diagnosis of SAP in early stages of AP.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis

Yang

Huang

et al. 2017

Sci Rep

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“…Organ failure status was calculated using the Marshall score. In this scoring, if patients receive ≥ 2 points, they are accepted as having developed organ failure [12]. All patients with AP diagnosis were monitored and treated according to the evidence-based AP management guidelines of the International Association of Pancreatology and American Pancreatic Association (IAP/APA) [13].…”

Section: Definition Of Acute Pancreatitis Severitymentioning

confidence: 99%

Effect of abdominal fat distribution on severity of acute pancreatitis

Beydogan¹,

Gülle²,

Gezer³

et al. 2021

ceh

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Aim of the study: Obesity is a well-determined risk factor for acute pancreatitis. Increased visceral fat has been shown to increase the proinflammatory environment experienced by patients. In this study, we aimed to research the correlation between abdominal fat distribution parameters measured with computed tomography (CT) and severity of acute pancreatitis (AP). Material and methods:The study included patients monitored due to AP in the internal medicine clinic of GOP Education and Research Hospital from January 2015 to December 2018. The Acute Physiology and Chronic Health Evaluation (APACHE) score, the Imrie score and the Bedside Index of Severity in Acute Pancreatitis (BISAP) scores were calculated. Advanced image processing analysis software (INFINIT Xelis, v 1.0.6.3) was used to calculate individual abdominal fat distribution parameters from CT screening with division of abdominal tissues. Measurements were performed from -50 to -250 Hounsfield units (HU) between vertebrae L2-L3. Results: When mild and moderate AP groups were compared, there were statistically significant differences in duration of hospital stay and scoring (APACHE, Imrie and BISAP) (p < 0.001), while there were no significant differences in abdominal fat distribution parameters (p > 0.05). There was no significant correlation of visceral and subcutaneous fat volumes with development of systemic complications, while a significant correlation was identified for visceral to total fat tissue area ratio (VTR) with local complications (p < 0.001). Pearson correlation analysis found no correlations of mortality and pancreatitis severity with visceral (VFA) and subcutaneous fat area (SFA) (p > 0.05). Positive correlations were identified for VFA with Imrie, BISAP and APACHE scores (p < 0.01), and positive correlations were identified for visceral adipose tissue (VAT) with visceral to subcutaneous fat ratio (VSR) and APACHE scores (r = 0.256 and 0.252, respectively, p < 0.001). Positive correlations were identified for VTR and VSR ratios with BISAP scores (r = 0.266 and r = 0.277, respectively, p < 0.001). Conclusions: In patients with AP diagnosis and abdominal CT scans, increased VFA and VTR ratio were found to be associated with increased AP clinical scores with no significant correlation identified in terms of local/systemic complication development. Our study shows that VFA is linked to AP clinical scoring systems and should be included in AP predictive scoring systems.

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“…Early complications i.e within 2 weeks of the attack are biliary obstruction, haemorrhage, extensive sterile necrosis, infection of the necrosis, peritonitis, multi-organ failure, deterioration, Wirsung rupture [31]. Variables found to be related to systemic complications were the APACHE II score as well as Sequential Organ Failure Assessment (SOFA) and Marshall scores [32] greater than 3. The variables related to mortality were SOFA score > 3, leukocytic count > 19,000mm -3 , CRP > 19.5 mg/dL and length of hospital stay were related to necrotizing pancreatitis [33].…”

Section: Severity Of Ap Atlanta Criteria (1993) Atlanta Revision (2013)mentioning

confidence: 99%

A glance at Acute Pancreatitis (AP)

Marzaban

2017

GHOA

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Severity assessment of acute pancreatitis: applying Marshall scoring system

Cited by 10 publications

References 21 publications

A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis

A reduced lymphocyte ratio as an early marker for predicting acute pancreatitis

Effect of abdominal fat distribution on severity of acute pancreatitis

A glance at Acute Pancreatitis (AP)

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