Severe sequelae of erythema multiforme: three cases

Abstract

References

A large epidemiological study of erythema multiforme in France, with emphasis on treatment choices

“…D ear E ditor , Erythema multiforme (EM), related to infectious agents (herpes simplex virus, Mycoplasma pneumoniae or idiopathic), is characterized by target lesions and is classified as minor or major according to the mucous membrane involvement . Severe cases can result in significant morbidity, pain, impaired food intake, hospitalization and sequelae . Symptomatic treatment is a key point in management of acute flares of EM.…”

Comment on ‘Bronchiolitis obliterans as a long‐term sequela of Stevens–Johnson syndrome and toxic epidermal necrolysis in children’

“…It is high time that young researchers are made aware of such conferences to prevent them from getting bamboozled. 4 reported severe long-term fibrotic sequelae of EMM in three patients, all of whom developed corneal complications with varied severities. M. pneumoniae was the trigger in two of them.…”

“…Extracutaneous aseptic neutrophilic infiltrate is one of the characteristics of the ND and is also called neutrophilic disease. Bucchia et al 4 performed a retrospective study of 27 paediatric patients with ND (SS and pyoderma gangrenosum) between 1998 and 2017, who were followed up for 26.3 months from the diagnosis of ND. The authors noted that the presence of atypical forms of ND, including overlap ND and association ND are frequent in paediatric patients, especially in infants.…”

“…Severe respiratory distress with no infectious aetiology was observed in three infants (aged 1, 6 and 8 months) at disease onset, before development of ND, and required noninvasive ventilation for two. 4 In the literature, cardiac manifestations of ND have been almost exclusively in patients diagnosed with SS…”

Erythema Multiforme: Etiology, Pathogenesis and Clinical Aspects

“…Эти проблемы иногда затрудняют морфологическую диагностику заболевания. Самые ранние проявления МЭЭ обычно представляют собой круглые, эритематозные, отечные папулы, окруженные участками просветления, которые могут напоминать укусы насекомых или папулезную крапивницу[28]. Эти папулы увеличиваются, и развиваются концентрические изменения морфологических признаков и окраски, что приводит к формированию хорошо известных мишеневидных очагов[29].…”