Severe postoperative intracranial hemorrhagic complications in a neurosurgical patient with von Willebrand disease not diagnosed before surgery (a case report and literature review)

Abstract

The article describes a rare clinical case of a patient with previously undiagnosed von Willebrand disease and basal meningioma; an intracranial neurosurgical intervention was complicated by delayed intracranial hematomas, both at the resected tumor site and distantly. The diagnosis of von Willebrand disease was established only after special hematology tests and only after surgery. Despite the use of specific therapy, the patient died due to intracranial hemorrhagic complications in the postoperative period. The paper discusses the problem of preoperative diagnosis of asymptomatic hemostasis disorders in neurosurgical patients and potential ways of its solution.

Dental extraction in a patient with undiagnosed Von Willebrand’s Disease: a case report

“…1 Importantly, these patients can have unexpected intra-and post-operative haemorrhage when undergoing surgery. While there are reports of life-threatening blood loss in other surgical specialities 2,3 such presentations in dentistry are thankfully rare. We report a case of routine exodontia and ensuing complications in a patient with undiagnosed vWD.…”