Dental extraction in a patient with undiagnosed Von Willebrand’s Disease: a case report

Abstract

Dental extractions are a common part of general dental practice. While dentists routinely screen for medical contraindications during the preoperative assessment, undiagnosed coagulopathies have the potential to severely complicate a seemingly routine extraction. We report a case of surgical removal of a mandibular third molar in a patient with undiagnosed Von Willebrand Disease.

The Presence of Periodontitis in Patients with Von Willebrand Disease: A Systematic Review

“…The most important role of this glycoprotein is to adhere to coagulation factor VIII, platelets and damaged subendothelium [5], as reported in Figure 1. Clinical signs of von Willebrand disease include nasal, conjunctival, or oral mucosal bleeding [4][5][6], persistent bleeding after minor trauma or dental extractions [7], excessive blood loss during menstrual periods [8], or bleeding of the gastrointestinal mucosa [9]. Among other systemic conditions that can coexist with periodontal disease, hemophilia expressed by VWD is known to affect the periodontal tissue [10].…”