Severe Mycoplasma pneumoniae infections with prolonged fever in a child: Delayed treatment is as important as macrolide resistance

Sim, Jun Yi; Chang, Yin‐Cheng; Chen, Wei-Yu; Chou, Yun; Hsu, Wei-Yun; Chen, Yu-Chin; Chang, Tu‐Hsuan

doi:10.1016/j.jmii.2020.04.014

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…From 2018 to 2020, we encountered an outbreak of M. pneumoniae among children in Taiwan with longer hospitalizations, greater use of inappropriate antibiotics, and more refractory diseases. 27 , 28 During this outbreak, macrolide resistance increased from 24% to 77%, predominantly in sequence type (ST) 3 and 17. 4 , 29 Despite multiplex PCR not being able to detect macrolide resistance and STs, the outbreak in early 2020 might belong to the same strains.…”

Section: Discussionmentioning

confidence: 98%

Circulating pediatric respiratory pathogens in Taiwan during 2020: Dynamic change under low COVID-19 incidence

Sim

Chen

Hsu

et al. 2022

Journal of Microbiology, Immunology and Infection

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Section: Discussionmentioning

confidence: 98%

Circulating pediatric respiratory pathogens in Taiwan during 2020: Dynamic change under low COVID-19 incidence

Sim

Chen

Hsu

et al. 2022

Journal of Microbiology, Immunology and Infection

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“…Typically, M. pneumoniae causes mild respiration infections with potential extra-pulmonary manifestations. However, increased clinical severity and extrapulmonary manifestations have been reported to be associated with delayed effective treatment for macrolide-resistant M. pneumoniae ( 7 , 8 ). In this case, a low sequence number of M. pneumoniae with a macrolide-resistant gene, A2063G on the 23S rRNA, was detected.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Mycoplasma pneumoniae-induced fulminant myocarditis in a 15-year-old male leading to cardiogenic shock and electrical storm

Zhu,

Hu,

et al. 2024

Front. Cardiovasc. Med.

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Mycoplasma pneumoniae (M. pneumoniae) is a well-recognized pathogen primarily associated with respiratory tract infections. However, in rare instances, it can lead to extrapulmonary manifestations, including myocarditis. We present a case of a 15-year-old male who developed fulminant myocarditis, cardiogenic shock, and cardiac electrical storm attributed to M. pneumoniae infection. He underwent a combination of intra-aortic balloon pump (IABP) and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiac support, ultimately surviving despite the intracardiac thrombus formation and embolic stroke. Following comprehensive treatment and rehabilitation, he was discharged in stable condition. This case underscores the importance of considering atypical pathogens as potential etiological factors in patients presenting with cardiac complications, especially in the adolescents. It also emphasizes the need for clinical vigilance and effective support for potential cardiac complications arising from M. pneumoniae infection.

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Pediatric parapneumonic effusion before and after national pneumococcal vaccination programs in Taiwan

Sim

Chang

et al. 2020

Journal of the Formosan Medical Association

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Severe Mycoplasma pneumoniae infections with prolonged fever in a child: Delayed treatment is as important as macrolide resistance

Cited by 4 publications

References 5 publications

Circulating pediatric respiratory pathogens in Taiwan during 2020: Dynamic change under low COVID-19 incidence

Circulating pediatric respiratory pathogens in Taiwan during 2020: Dynamic change under low COVID-19 incidence

A Case Report of Mycoplasma pneumoniae-induced fulminant myocarditis in a 15-year-old male leading to cardiogenic shock and electrical storm

Pediatric parapneumonic effusion before and after national pneumococcal vaccination programs in Taiwan

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