Severe COVID-19 and Retina: Are There Any Retinal Manifestations?

Gündoğan, Medine; Kiliç, Soner; Göktaş, Sertan; Vural, Esra; Sirem, Muhammed Raşit; Ünal, Sefa; Çelik, İ̇lhami

doi:10.1055/a-1525-2420

Cited by 3 publications

(3 citation statements)

References 19 publications

(41 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, we found no significant differences in any of these parameters. Gündoğan et al (22) also investigated the posterior segment involvement of the COVID-19 and concluded the same with our study. However, Pereira et al (23) reported cotton wool spots and flame-shaped hemorrhages on the retina of the COVID-19 patients.…”

Section: Discussionsupporting

confidence: 90%

COVID -19 hastalarında arka segment optik koherens tomografi bulguları

KOÇKAR¹,

Yılmaz

SEZGİN³

et al. 2023

Hitit Medical Journal

View full text Add to dashboard Cite

Purpose: COVID – 19 which is still the leading health problem in the world, is not yet fully understood, therefore the study aims to investigate the posterior segment of the eye in patients with COVID – 19 using optical coherence tomography (OCT). Materials and Methods: The present study was designed prospective and cross-sectional. Patients with a positive test result of COVID – 19 and healthy controls who were older than 18 years were included in the study. Excluded from the study were the patients with any systemic comorbidity and ocular disease. The demographic and clinical data, including ocular findings and the OCT data, including hyper-reflective (HR) lesions, retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and macular thicknesses (MT) were recorded as outcomes and analyzed. Results: Twenty patients with SARS-CoV-2 and 20 healthy subjects were included in this study. There was no difference between COVID -19 patients and healthy controls in terms of the RNFL, GCC, and macular thicknesses (P > 0.05). HR lesions were detected in 18(45%) eyes of 9(45%) patients with COVID – 19 and 15(37,5%) eyes of 8(40%) healthy subjects’ retinae with no significant difference between groups (P = 0.165). Conclusions: Hyper-reflective lesions could only be retinal vessels' tangential cuts seen in OCT B-Scans. There was not enough data that could indicate posterior segment involvement of COVID – 19.

show abstract

Section: Discussionsupporting

confidence: 90%

COVID -19 hastalarında arka segment optik koherens tomografi bulguları

KOÇKAR¹,

Yılmaz

SEZGİN³

et al. 2023

Hitit Medical Journal

View full text Add to dashboard Cite

show abstract

“… p > 0.05 30 Erogul O. et al >2022 61 Comparative cross-cutting 64 eyes 18 46 PostCOVID-19 >1 month Investigate retinal microvascular changes Decreased vascular density p < 0.05 31 Aydemir E. et al >2021 62 Prospective cross-sectional 39 eyes 20 19 PostCOVID-19 Assess retinal microcirculation Decreased vascular density p < 0.05 32 Goyal M. et al >2021 63 Case series 14 eyes >7 patients 8 6 COVID-19 Describe retinal manifestations Acute macular neuroretinopathy, central serous choroidopathy, fungal endophthalmitis, candida retinitis, prefoveolar hemorrhages. – 33 Yagmur A. et al >2022 64 Comparative cross-cutting 34 eyes – – PostCOVID-19 Researching neurodegenerative effects Thinning of ganglion cell layer and inner plexiform cells p < 0.05 34 Gündogan M. et al >2022 65 Comparative cross-cutting 464 eyes 312 152 COVID-19 Investigating retinal lesions No findings …”

Section: Resultsmentioning

confidence: 99%

Alterations in the optic nerve and retina in patients with COVID-19. A theoretical review

Cevallos

Vásquez²

2023

Archivos de la Sociedad Española de Oftalmología (English Editi

View full text Add to dashboard Cite

“…In subsequent studies, different results were found at different rates [13 -15]. As a matter of fact, some studies have not found significant evidence of retinal lesions in COVID-19 patients [16,17]. Today, cases of COVID-19 are increasing all over the world and new mutations are added [18].…”

Section: Introductionmentioning

confidence: 99%

Retinal Findings in Hospitalized COVID-19 Patients, Is Routine Ophthalmological Examination Required after Discharge? Prospective Case-Control Study

Akalin

Kalkişim

Günay

et al. 2023

Klin Monbl Augenheilkd

View full text Add to dashboard Cite

Objectives To investigate retinal findings by comparing patients hospitalized for COVID-19 with the control group. Methods In this prospective study, 188 eyes of 94 recovered COVID-19 patients and 108 eyes of 54 healthy participants as a control group were evaluated. Patients were divided into three groups, those with mild, moderate, and severe COVID-19. Refractometry, tonometry, optical biometry, optical coherence tomography (OCT) measurements, and complete ophthalmological examinations were performed on healthy volunteers and COVID-19 patients on average 2 weeks after discharge. Pulse O2 and vital parameters were also assessed. Primary outcomes were evaluated, such as retinal findings, and secondary outcomes as retinal thickness, choroidal thickness (CT), retinal nerve fiber layer thickness, and ganglion cell layer thickness. Results There was no difference between the groups in terms of demographic data, ocular biometry, and intraocular pressure (p > 0.05). Pulse O2 was lower in the study group (p < 0.001). Retinal findings were detected in 68 (36.1%) of 188 eyes in the study group and 28 (25.9%) of 108 eyes in the control group (p = 0.07). The two most common retinal findings were hypertensive retinopathy and retinal pigment epithelium alterations and/or drusen in both groups. In OCT measurements, significant thinning was observed in nasal macular thickness and superior 2 mm CT in the study group compared to the control group (p < 0.05). In patients divided into subgroups according to disease severity, no significant difference was found between the groups in any OCT parameter (p > 0.05). Conclusion It has been observed that COVID-19 infection does not cause a specific and sensitive finding in the ocular tissues, especially the retina, and does not produce a reproducible measurement result. Recommending routine eye exam after COVID-19 does not seem cost-effective.

show abstract

Severe COVID-19 and Retina: Are There Any Retinal Manifestations?

Cited by 3 publications

References 19 publications

COVID -19 hastalarında arka segment optik koherens tomografi bulguları

COVID -19 hastalarında arka segment optik koherens tomografi bulguları

Alterations in the optic nerve and retina in patients with COVID-19. A theoretical review

Retinal Findings in Hospitalized COVID-19 Patients, Is Routine Ophthalmological Examination Required after Discharge? Prospective Case-Control Study

Contact Info

Product

Resources

About