Severe coronavirus disease 2019 in children and young adults

Wilkes, Meredith; Issa, Rula; Aluf, Anna; Beliard, Kara; Yau, Mabel; Rapaport, Robert; Ebekozien, Osagie

doi:10.1016/j.jpeds.2020.06.061

Cited by 2 publications

(2 citation statements)

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“…21 Among them, diabetes, obesity, and several other chronic disorders, have unanimously emerged as predictors of unfavorable outcomes. [21][22][23][24][25][26][27][28][29] For instance, two large US cohorts have recently shown the relationship between the severity of COVID-19 and comorbidities. Kompaniyets et al 30 reported data from 800 US hospitals with a cohort of about 43,000 children and adolescents.…”

Section: Discussionmentioning

confidence: 99%

Clinical Outcomes of Omicron Variant (B.1.1.529) Infection in Children and Adolescents Hospitalized With COVID-19 in Brazil With Observational Data on the Efficacy of the Vaccines in Adolescents

Oliveira¹,

Oliveira²,

Silva³

et al. 2022

Pediatric Infectious Disease Journal

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Oliveira et al responsibility for the integrity of the data and the accuracy of the data analysis. FIGURE 3. Predictors of death among 7442 participants who tested positive for SARS-CoV-2 during the omicronpredominant period. Data are from the competing-risk survival analysis (A) Model for the entire cohort, adjusted hazard ratios. (B) Model for individuals 12-19 years of age, adjusted hazard ratios. Error bars indicate 95% CI. Unvaccinated children were assigned as the reference category.

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Section: Discussionmentioning

confidence: 99%

Clinical Outcomes of Omicron Variant (B.1.1.529) Infection in Children and Adolescents Hospitalized With COVID-19 in Brazil With Observational Data on the Efficacy of the Vaccines in Adolescents

Oliveira¹,

Oliveira²,

Silva³

et al. 2022

Pediatric Infectious Disease Journal

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“…Five American studies on 800 children with an average age of approximately 12 years indicated that almost all children with COVID-19 experienced at least one GI symptom of vomiting and diarrhea (6,(14)(15)(16)(17). In Kainth MK et al's study, in addition to diarrhea and vomiting, 40% and 11% of children had anorexia and abdominal pain, respectively (14).…”

Section: Gastrointestinal Symptoms In Children With Covid-19 Infectionmentioning

confidence: 97%

Gastrointestinal Symptoms and Hepatopancreatic Involvement in COVID-19 Children: A Narrative Review

Mehrabani

Nikpour

Moslemi

2022

JPR

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Background: To the best of our knowledge, limited studies explored gastrointestinal (GI) symptoms and hepatopancreatic involvement in children with coronavirus disease 2019 (COVID- 19) infection. Objectives: This review study aimed to evaluate the GI symptoms and abnormal liver and pancreas function in children with COVID-19 infection. Methods: In this review study, databases of Scopus, PubMed, Google Scholar, and Web of Science were searched using the relevant keywords of “COVID-19,” “children,” “gastrointestinal,” “liver,” and “pancreas.” Descriptive and cross-sectional studies were reviewed in the current study, with the main focus on GI symptoms and elevated liver enzymes in children with COVID-19 infection. Results: Overall, 27 studies from countries of Iran, Spain, Turkey, Italy, and the United States were selected. Although the prevalence of GI symptoms varied in different studies, our review showed that most children with COVID-19 infection experienced GI symptoms. In addition to GI symptoms, there is the possibility of elevated liver enzymes, such as alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, and creatine phosphokinase in children with COVID-19 infection. Conclusions: COVID-19 infection may present various GI, hepatic, and pancreatic manifestations in children. The difference in the prevalence of these symptoms can probably be attributed to the geographical region of the study and the history of the disease.

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Severe coronavirus disease 2019 in children and young adults

Cited by 2 publications

References 1 publication

Clinical Outcomes of Omicron Variant (B.1.1.529) Infection in Children and Adolescents Hospitalized With COVID-19 in Brazil With Observational Data on the Efficacy of the Vaccines in Adolescents

Clinical Outcomes of Omicron Variant (B.1.1.529) Infection in Children and Adolescents Hospitalized With COVID-19 in Brazil With Observational Data on the Efficacy of the Vaccines in Adolescents

Gastrointestinal Symptoms and Hepatopancreatic Involvement in COVID-19 Children: A Narrative Review

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