Severe case of genital and perianal cutaneous Crohnʼs disease

Crohn’s disease presenting as vulvar edema in a 15-year-old girl

“…[5][6][7][8][9] Patients with vulval CD typically present with erythema and edema of the labia majora, but soon progress to extensive ulcer formation. 6 The labia majora and clitoris are involved in most cases, and there may be gross architectural destruction of the vulval region. In our case, erythema and edema of the labium majus were present, but there was no ulcer or architectural destruction in the vulval region.…”

Development of colonic inflammatory activity after colostomy in patients with exclusively skin perineal Crohnʼs disease

“…Also, such injuries usually occur after intestinal manifestation and not preceding, as occurred in this patient. 2 In such situations, in addition to conventional treatment with corticosteroids, antibiotics, immunosuppressants, and biologic therapy, the realization of a stoma is described as a saving option for many authors. [1][2][3][4] Despite the undoubted advantages of fecal diversion in patients with severe genital and perianal involvement, we must also consider the high rate of complications of these procedures.…”

“…2 In such situations, in addition to conventional treatment with corticosteroids, antibiotics, immunosuppressants, and biologic therapy, the realization of a stoma is described as a saving option for many authors. [1][2][3][4] Despite the undoubted advantages of fecal diversion in patients with severe genital and perianal involvement, we must also consider the high rate of complications of these procedures. Post et al 5 showed that the main indication for stoma in patients with celiac disease was genital and perianal fistulas; the complication rate of stoma was 31% versus 5% for colostomies and ileostomies, respectively.…”

Common and unusual urogenital Crohn’s disease complications: spectrum of cross-sectional imaging findings

“…Clinical presentation includes local swelling or ulcerations, and pelvic-perianal MRI detects these abnormalities as fluid-filled, peripherally enhancing structures usually associated with perianal fistulas (Fig. 9) [10,34,35]. Furthermore, exceptional cases of metastatic CD as solitary, non-healing ulcers or plaques involving the skin and subcutaneous planes of the penis and scrotum have been described [34].…”

“…9) [10,34,35]. Furthermore, exceptional cases of metastatic CD as solitary, non-healing ulcers or plaques involving the skin and subcutaneous planes of the penis and scrotum have been described [34].…”