Severe calcinosis cutis with cutaneous ulceration in juvenile dermatomyositis

Meher, Bijay Kumar; Mishra, Pradeep; Sivaraj, Pradeep; Padhan, Prasanta

doi:10.1007/s13312-014-0531-8

Cited by 6 publications

(2 citation statements)

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“…Moreover, calcinosis cutis can develop in some rheumatological diseases, such as juvenile dermatomyositis and systemic sclerosis. When it appears with some rheumatologic diseases, it could be due to severity and delayed treatment of the disease or related to some genetic polymorphism [ 7 , 8 ]. The exact type of calcinosis cutis should be accurately identified for proper treatment and management [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…It can be confirmed by applying hematoxylin and eosin or von Kossa silver stain to an alcohol-fixed smear in which it will show calcium deposits [ 1 , 4 ]. Radiologic findings in plain radiograph may appear as multiple linear and stippled calcifications subcutaneously [ 7 ], as well as increased reuptake in bone scan suggesting heterotrophic ossification or myositis ossificans [ 9 ]. The diagnosis is frequently mistaken for cellulitis, osteomyelitis, arthritis, abscess, periostitis, and thrombophlebitis [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

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Iatrogenic calcinosis cutis in 9-month-old baby boy: a case report

2022

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Background Calcinosis cutis is a rare condition, characterized by an accumulation of calcium salts in the skin and subcutaneous tissue. There are several types of this condition, including dystrophic, metastatic, idiopathic, calciphylaxis, and iatrogenic calcinosis cutis. The type related to our case is iatrogenic calcinosis cutis, and one its possible causes is calcium intravenous infusion. Physicians should be aware of this condition when giving calcium infusion. Case presentation Here we report the case of a 9-month-old Arabic - Saudi baby boy, who presented with abnormal movement for 1 day. Upon further investigation, his abnormal movement was found to be a manifestation of hypocalcemia and vitamin D deficiency. He was treated with intravenous calcium gluconate. Later, he had a treatment-related complication of intravenous calcium at the site of venipuncture causing swelling, which was initially soft but progressed to hard, over the left hand. Eventually, he was diagnosed with a case of iatrogenic calcinosis cutis due to intravenous calcium treatment. Conclusion There are multiple differential diagnoses of calcinosis cutis, as it resembles many other conditions. Careful history-taking, physical examination, and other investigations, such as radiological investigations, will aid in reaching a more accurate diagnosis and, thus, early treatment and intervention. Frequently checking the intravenous line and diluting the intravenous calcium may help reduce the occurrence of iatrogenic calcinosis cutis.

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Section: Discussionmentioning

confidence: 99%