Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Mimicking as Pulmonary Tuberculosis in an Inmate

Akbar, Habibullah; Kahloon, Rehan; Akbar, Sobia; Kahloon, Arslan

doi:10.7759/cureus.8464

Cited by 5 publications

(11 citation statements)

References 10 publications

(14 reference statements)

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“…Furthermore, the suspicious radiological findings on presentation alerted the physicians for additional etiology other than COVID‐19 alone. Therefore, most of our patients, along with reported cases of coinfection of TB and COVID‐19, 6‐9,13,14 had chronic symptoms and hence were likely to have undiagnosed former TB and subsequent COVID‐19 that led them to present to hospitals, rather than having TB deactivation secondary to COVID‐19 15 …”

Section: Discussionmentioning

confidence: 96%

New disease and old threats: A case series of COVID‐19 and tuberculosis coinfection in Saudi Arabia

Shabrawishi

AlQarni

Ghazawi

et al. 2021

Clinical Case Reports

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Section: Discussionmentioning

confidence: 96%

New disease and old threats: A case series of COVID‐19 and tuberculosis coinfection in Saudi Arabia

Shabrawishi

AlQarni

Ghazawi

et al. 2021

Clinical Case Reports

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“…In the few published reports of SARS-CoV-2/MBT coinfection, the TB diagnosis was made with a tuberculin test. Akbar et al reported negative results of an acid-fast bacillus smear and culture and of an QuantiFERON-TB Gold test in the patient they described [ 6 ]. In our case, the diagnosis was made with bacilloscopy and the GeneXpert MTB/RIF test.…”

Section: Discussionmentioning

confidence: 99%

“…On imaging studies of patients with COVID-19, ground-glass opacities, consolidations with identifiable air bronchogram, and sequelae of previous cavitating lesions have been reported [ 19 ]. On CT, enlarged mediastinal lymph nodes and pulmonary nodules have been identified in these individuals [ 6 ]. COVID-19 also can manifest on chest CT as a crazy paving pattern or in airway changes or a reverse halo sign.…”

Section: Discussionmentioning

confidence: 99%

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COVID-19 and Tuberculosis Coinfection in a 51-Year-Old Taxi Driver in Mexico City

Orozco¹,

Tinajero²,

Vargas³

et al. 2020

Am J Case Rep

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Patient: Male, 51-year-old Final Diagnosis: COVID-19 Symptoms: Anosmia • dysgeusia • nocturnal diaphoresis Medication: — Clinical Procedure: — Specialty: Infectious Diseases Objective: Rare co-existance of disease or pathology Background: Coinfection with severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) and Mycobacterium tuberculosis (MBT) has been reported, albeit rarely, in various parts of the world and has received attention from health systems because up to one-third of the world’s population has been infected with SARS-CoV-2. Mexico was not included in the first-ever report on a global cohort of patients with this coinfection. We report on a case of SARS-CoV-2/MBT coinfection in a 51-year-old taxi driver from Mexico City that underscores the importance of rapid and accurate laboratory testing, diagnosis, and treatment. Case Report: We present the case of a man in the sixth decade of life who was admitted to the National Institute of Respiratory Diseases (INER) with a diagnosis of COVID-19 pneumonia, which was confirmed by nasopharyngeal exudate using real-time polymerase chain reaction (RT-PCR) for the identification of SARS-CoV-2. Findings from imaging studies suggested that the patient might be coinfected with MBT. That suspicion was confirmed with light microscopy of a sputum sample after Ziehl-Neelsen staining and when a Cepheid Xpert MTB/RIF assay, an automated semi-quantitative RT-PCR assay, failed to detect rifampicin resistance. The patient was discharged from the hospital 10 days later. Conclusions: The present report underscores the importance of using validated molecular diagnostic tests to identify coin-fections in areas where there is a high prevalence of other causes of pneumonia, such as MBT, as a way to improve clinical outcomes in patients during the COVID-19 pandemic. While it is imperative to control the COVID-19 pandemic, the medical community must not forget about the other pandemics to which populations are still prey, and tuberculosis is one of them. We must remain alert to any clinical subtleties so as to ensure timely and accurate diagnosis and stay one step ahead of COVID-19.

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“…ST-Segment Elevation Myocardial Infarction (STEMI) is one of the most common causes of hospitalization in cardiology emergency and is related to high rates of mortality even in the presence of advanced facilities. In Pakistan there is lack of epidemiological data in respect to acute myocardial infarction but data from USA has shown approximately 1.5 million people suffered from acute myocardial infarction in a year and the proportion STEMI is on constant rise [1]. Type 2 Diabetes mellitus (T2DM) is a metabolic disease affecting more than 34 million people in America means every 1 person is affected out of 10.…”

Section: Introductionmentioning

confidence: 99%

In Hospital Frequency of Heart Failure in STEMI after Thrombolysis in Patient with Diabetes

Mueed

Rathi

Kazi

et al. 2021

JPRI

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Objective: To determine the frequency of heart failure after thrombolysis in STEMI patients with diabetes mellitus. Methodology: Through a prospective study we have enrolled all the diabetic patients who presented with acute ST-Segment Elevation Myocardial Infarction (STEMI) having age more than 35 years and less than 70 years who underwent pharmacological revascularization both males and females were included in this study. Patients with previous history of revascularization, end stage kidney, liver or heart disease, known advanced valvular heart disease, pregnant women, and those who develop serious complication related to streptokinase were excluded from our study. Echocardiography was done immediately after thrombolysis then after 3 days and then before discharge of the patients to determine the frequency of heart failure. Baseline and clinical data were entered and analysed using SPSS and a chi square test and p-value ≤0.05 was considered as significant. Results: A total of 175 patients were finally analysed and most of them were males as compared to females, 63.42% (N = 111) vs. 36.57% (N = 64), respectively. Mean age and SD of the patients was 55.90±10.49 years and mean duration of DM was 12.95±8.40 years. The overall frequency of heart failure in patients with post-STEMI was 56% (N = 98) and their mean ejection fraction was 38.46±8.20%. Frequency of heart failure in diabetic post-STEMI thrombolysed patients was significantly observed higher with increased age, increased duration of diabetes mellitus, hypertension, and smoking (p≤0.05). Conclusion: High prevalence of heart failure was observed in diabetic patients admitted with acute STEMI and underwent thrombolysis. The burden is even higher in males having age more than 55 years.

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Mimicking as Pulmonary Tuberculosis in an Inmate

Cited by 5 publications

References 10 publications

New disease and old threats: A case series of COVID‐19 and tuberculosis coinfection in Saudi Arabia

New disease and old threats: A case series of COVID‐19 and tuberculosis coinfection in Saudi Arabia

COVID-19 and Tuberculosis Coinfection in a 51-Year-Old Taxi Driver in Mexico City

In Hospital Frequency of Heart Failure in STEMI after Thrombolysis in Patient with Diabetes

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