Seven year follow‐up of 300 young drug abusers

Haastrup, S.; Jepsen, P.

doi:10.1111/j.1600-0447.1984.tb01239.x

Cited by 46 publications

(21 citation statements)

References 4 publications

(5 reference statements)

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“…This is the same proportion as in other studies (8,23). But it is also possible to find a suicide-prone profile or to find predictive factors behind this kind of fatal outcome.…”

Section: Mortalitysupporting

confidence: 79%

Fatal outcome in drug addiction

Tunving

1988

Acta Psychiatr Scand

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A sample of 524 young drug addicts consecutively treated at a special hospital ward has been followed by registers for an average of 10 years. A total of 62 were found to have died drug-related deaths at an average age of 28 years; 19 of them had committed suicide. Representativeness of the sample is investigated. Sex and choice of drugs were predictive factors behind fatal outcome: male opiate addicts died 5.4 times and male amphetamine abusers 2.5 times as often as expected. The males were exposed to greater risk than the females. Those who committed suicide had an hereditary disposition for mental disturbances, especially affective disorders. Lethal substances proved to be opiates, barbiturates and alcohol and/or other psychotropic preparations. Signs of heart disease were often found in the overdose cases. Most of the addicts who died were in a compulsive stage of the drug career, but some were abstaining or trying to abstain from drugs. A critical period seems to be at 26-28 years of age, a period when the abuse seems to be most intense and compulsive, the suicide risk is high and the efforts to abstain from drugs most serious and hazardous.

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“…This is the same proportion as in other studies (8,23). But it is also possible to find a suicide-prone profile or to find predictive factors behind this kind of fatal outcome.…”

Section: Mortalitysupporting

confidence: 79%

Fatal outcome in drug addiction

Tunving

1988

Acta Psychiatr Scand

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“…Follow-up studies have found that this risk continues for many years after the diagnosis of heroin dependence is made (Bargagli, Sperati, Davoli, Forastiere, & Perucci, 2001;Goldstein & Herrera, 1995;Haastrup & Jepsen, 1984;Hser, Anglin, & Power, 1993;Sanchez et al, 1995), indicating that heroin dependence may be regarded as a chronic condition. In fact, opioid addiction is currently defined as a bchronic, relapsing disorder Q (Dole & Nyswander, 1967;Leshner, 1998;McLellan, Lewis, O'Brien, & Kleber, 2000).…”

Section: Introductionmentioning

confidence: 95%

An overview of systematic reviews of the effectiveness of opiate maintenance therapies: available evidence to inform clinical practice and research

Amato¹,

Davoli²,

Perucci³

et al. 2005

Journal of Substance Abuse Treatment

487

362

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“…There are some indications, however, that IVDUs are at increased risk of overall mortality, deaths from overdose, trauma, infectious diSeaseS. [6][7][8][9][10][11][12] This study describes the pattern ofmortality in a large cohort of IVDUs in Rome during the period of transition into the "AIDS era. "…”

Section: Inrodictonmentioning

confidence: 99%

Mortality of intravenous drug users in Rome: a cohort study.

Perucci¹,

et al. 1991

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A historical cohort study was carried out in Rome to examine overall and cause-specific mortality among intravenous drug users (IVDUs). A total of 4200 IVDUs (3411 men and 789 women) enrolled in methadone treatment centers between 1980 and 1988 were studied. There were 239 deaths during the follow-up period. The overall SMR was 10.10 in the entire cohort (95% confidence interval, 8.86-11.47), 9.30 in males and 18.07 in females. A large excess of mortality in both sexes was found for infectious, circulatory, respiratory, and digestive diseases as well as for violence, overdose, AIDS, and unknown or ill-defined causes. Tumors and suicide were excessive only in males. Deaths due to drug overdose, violence or trauma, and cirrhosis accounted for 63.6%, AIDS for 7.1%, endocarditis and other bacterial infections for 7.1%, and neoplasms for 3.8% of total mortality. These findings document serious health consequences of drug abuse in Italy.

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Seven year follow‐up of 300 young drug abusers

Cited by 46 publications

References 4 publications

Fatal outcome in drug addiction

Fatal outcome in drug addiction

An overview of systematic reviews of the effectiveness of opiate maintenance therapies: available evidence to inform clinical practice and research

Mortality of intravenous drug users in Rome: a cohort study.

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