Sesquiterpene lactones and other constituents of Tanacetum species

González, Antonio G.; Barrera, Jaime Bermejo; Méndez, Jorge Triana; Sánchez, Mariana López; Martínez, José Luis Eiroa

doi:10.1016/0031-9422(92)83157-t

Cited by 18 publications

(9 citation statements)

References 8 publications

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“…colorless needles, rn.p. 183.6 °C, [aID: + 133.83 (c 0.370, CHCI3), IR (CHCI3):Vmax = 1768, 1742, 1672, 1240 m/z = 264 [MJ(6), 246 (70), 228 (38), 173 (67), 161 (59), 119 (66), 97 (100), 1H-NMR was in agreement with references (11,…”

supporting

confidence: 87%

“…4a,6a-Dihydroxyeudesman-8,1 2-olide was acetylated with Ac20/pyridine at room temperature. The reaction product was purified by recrystallization (MeOH) and identified as 6aacetoxy-4a-hydroxyeudesman-8J3,12-olide (1 a) by its 1H-NMR spectrum (6). 1H,s,5.27 (1H,dd,J= 11.6,2.0Hz,, 4.51 (IH, ddd,J = 6.4,5.6,1.6Hz, H-8), 2.97 (1H, dd,J = 5.6, 9.6 Hz, H-7), 2.08 (1H, d,J = 15.4,1.6Hz, H-9), 1.13 (3H, s, H-15), 1.01 (3H, s, H-14), 2.05 (3H, s, H-17), 13CNMR see Table 2.…”

Section: Extraction and Isolationmentioning

confidence: 99%

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Cytotoxic Sesquiterpene Lactones fromInula britannica

Park¹,

Kim²

1998

Planta Med

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supporting

confidence: 87%

Section: Extraction and Isolationmentioning

confidence: 99%

Cytotoxic Sesquiterpene Lactones fromInula britannica

Park¹,

Kim²

1998

Planta Med

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“…sivasicum [41] Partenolide T. parthenium [40] Spiciformine T. densum ssp. sivasicum [41] Tamirin T. vulgare [38] Tanacin Tatridin A T. ptarmicaeflorum [45] Deacetyltulipinolide-1-β,10-α-epoxide T. densum ssp. amani [46] Artecanin T. parthenifolium [47] Canin T. macrophillum [48] Apigenin T. albipannosum [49] Luteolin T. cinerariifolium [50] Hispidulin T. sibiricum [51] Quercetin T. vulgare T. vulgare [52] Axillarin Naringenin T. sibiricum [53] Table 5 and according to previously published procedure.…”

Section: Compound Species Ref Dentatin Amentioning

confidence: 99%

Composition and potential of Tanacetum haussknechtii Bornm. Grierson as antioxidant and inhibitor of acetylcholinesterase, tyrosinase, and α-amylase enzymes

Yur

Tekin

Göğer

et al. 2017

International Journal of Food Properties

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The phytochemical composition of essential oils and extracts of Tanacetum haussknechtii were investigated with GC-FID-MS and LC-MS/MS techniques and evaluated against oxidation, acetylcholinesterase, tyrosinase, and α-amylase enzymes. The major volatile constituents of T. haussknectii were found to be αand β-pinene, and borneol. Caffeoylquinic acid derivatives and flavonoids were detected in the aqueous, alcohol, and ethyl acetate extracts. In DPPH assay, the methanol extracts exhibited the highest activity. TEAC assay resulted with superiority of all methanol and the capitula ethyl acetate extract. In β-carotene bleaching assay, linoleic acid was the best protected by the ethyl acetate extract of flower. The flower oil inhibited higher acetylcholinesterase activity than the remaining extracts. The flower ethyl acetate extract was found as the most effective inhibitor of α-amylase. The herb and the leaf+stem water extracts possess highest inhibitory effect on tyrosinase. ARTICLE HISTORY

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“…The extracts of T. parthenium L. contain a diverse range of compounds. Most of the studies report the analysis and quantitation of sesquiterpene lactones (parthenolide, santamarin, canin) and flavonoid content (santin, luteolin, apigenin) of the plant (Awang et al ., ; González et al ., ; Harborne et al ., ; Végh et al ., ). There are several reports on the composition of the essential oil of feverfew (Mirjalili et al ., ; Hendriks et al ., ; Banthrope et al ., ; Akpulat et al ., ; Haziri et al ., ; Izadi et al ., ), in which the main components were found to be camphor, camphene and trans‐ chrysanthenyl acetate.…”

Section: Introductionmentioning

confidence: 99%

Convergence chromatographic determination of camphor in the essential oil of Tanacetum parthenium L.

Végh

Riethmüller

Tóth

et al. 2016

Biomedical Chromatography

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Feverfew (Tanacetum parthenium L., Asteraceae) is a perennial medicinal plant which has been used to alleviate the symptoms of migraine, headache and rheumatoid arthritis and possesses numerous pharmacological activities. An ultra-high-performance supercritical fluid chromatographic method (UHPSFC) was developed and validated in accordance with the International Conference on Harmonization guidelines in order to determine the camphor content of the volatile oil, which was accurate, precise, robust and selective. The method was validated for specificity, accuracy (100.2%), repeatability and intermediate precision, linearity (r > 0.999), limit of detection (2.055 μg/mL), limit of quantification (6.228 μg/mL) and robustness. The common range of accuracy and linearity was between 0.125 and 1.000 mg/mL. Steam distillation was carried out in order to study the essential oil yield of three different T. parthenium L. samples originating from Hungarian medicinal herb collections. The camphor content of the essential oils from the aerial parts of feverfew samples from different origin was compared. Although the composition of the essential oil is well reported, a validated quantitative UHPSFC method for the determination of the constituents is presented herein for the first time.

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Sesquiterpene lactones and other constituents of Tanacetum species

Cited by 18 publications

References 8 publications

Cytotoxic Sesquiterpene Lactones fromInula britannica

Cytotoxic Sesquiterpene Lactones fromInula britannica

Composition and potential of Tanacetum haussknechtii Bornm. Grierson as antioxidant and inhibitor of acetylcholinesterase, tyrosinase, and α-amylase enzymes

Convergence chromatographic determination of camphor in the essential oil of Tanacetum parthenium L.

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