Sesquiterpene alcohols from Cryptomeria japonica and C. Fortunei leaf oil

Germacradienols in the essential oils of the Myrtaceae

“…Germacradienols are found in the extracts of a variety of plant species 1 -5 and are potentially the precursors of the cadinene and skeletally related sesquiterpenoids observed in the steam distillates of other species. 1 A similar situation has been proposed for germacrene D. 6,7 In this work, two germacradienols have been isolated and identified in the solvent extracts of members of the family Myrtaceae. These sesquiterpenes are the direct precursors of (C)-υ-cadinene, the cadinols and muurolols and other related sesquiterpenes observed in the steam distillates or (in some cases) the solvent extracts of the mature growth.…”

“…In this species and in many other members of the Myrtaceae (Table 1) these compounds are associated with the acid-solvolysis of a compound that was identified as germacrenol 1 (Figure 1) by establishing the basic skeleton using HMBC, HMQC and DQ-COSY experiments and by its characteristic mass spectrum, which exhibits a large base peak at m/z 81 ( Figure 2) 13,14 and by comparison of the 13 C-and 1 H-NMR data ( Table 2) with previous reports. 1,4,15,16 This compound has not been previously reported in the Myrtaceae, although reports of the presence of its breakdown products are not uncommon. 17 The basic assignments of the conformation and skeleton of germacrenol are detailed below.…”

Evaporation of volatiles from essential oils of Japanese conifers enhances antifungal activity

“…While there have been several reports in the literature concerning the biological activities of elemol and elemol-rich fractions (23,31), no reports have been published to date identifying elemol as the notable antifungal factor of C. japonica needle EO against wood decay fungi. It has been reported that elemol is formed from the thermal Cope rearrangement of hedycaryol during steam distillation (32), and that elemol and eudesmols represent transformed products in the EO of C. japonica, whereas hedycaryol represents as crude component of the EO (33). The results of present study therefore suggest that elemol-rich EOs as well as rich hedycaryol sources could be used as antifungal agent.…”

Germacra‐1(10),5‐dien‐4α‐ol in Fortunella sp. leaf oils

“…identification of the β isomer [germacra‐1(10),5‐dien‐4β‐ol] using NMR data has been reported in various essential oils or solvent extracts such as Cryptomeria japonica leaf oil; extract from soft coral of Nepheta sp., extract from the marine sponge Luffariella sp., extract from Juniperus communis sp. bemzspbaerzca . In contrast, the occurrence of the α isomer has been reported in a solvent extract of marine soft coral Lernnaliu ufricana and in the root oil from Peucedanum palustre , as well as in the solvent extract of fruits from Reneilmia cincinnata .…”