Germacra‐1(10),5‐dien‐4α‐ol in <i>Fortunella</i> sp. leaf oils

Sutour, Sylvain; Bradesi, Pascale; Luro, François; Casanova, Joseph; Tomi, Félix

doi:10.1002/ffj.3258

Cited by 6 publications

(2 citation statements)

References 36 publications

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“…Hydrolate extracts were chromatographed using a Grace Reveleris ® flash chromatography system using a linear gradient pentane/chloroform/methanol. The F19 fraction eluted with 20% chloroform in pentane contains 2.0813 g of cis-cis-p -menthenolide with a purity of 95% [ 36 , 38 , 39 ].…”

Section: Methodsmentioning

confidence: 99%

Anti-Quorum Sensing Activity of 12 Essential Oils on chromobacterium violaceum and Specific Action of cis-cis-p-Menthenolide from Corsican Mentha suaveolens ssp. Insularis

et al. 2018

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Quorum sensing (QS) is a bacterial communication mechanism used to express various survival or virulence traits leading to enhanced resistance. Chromobacterium violaceum is a commonly used strain that highlights anti-QS action of bioactive substances. Here, we wanted to see if 12 selected essential oils (EO) could exert anti-QS activity. We measured the sublethal minimal QS inhibitory concentration (MQSIC) by assessing violacein production of C. violaceum along with bacterial growth. To confirm the QS disruption, we also proceed to surface bacterial observations using scanning electron microscopy (SEM). We showed that cis-cis-p-menthenolide extracted and isolated from a plant endemic to occidental Mediterranean Sea islands, Mentha suaveolens ssp. insularis, acts as an inhibitor of violacein production and biofilm formation. Measured MQSIC was much lower than the minimal inhibitory concentration (MIC): 0.10 mg·mL−1 vs. 3.00 mg·mL−1. Moreover, disturbance of QS-related traits was confirmed by the degradation of C. violaceum biofilm matrix. There is a clear structure–activity relationship between cis-cis-p-menthenolide and anti-QS activity. Indeed, its isomer molecule (mintlactone) exerts a poor anti-QS action. These results indicate that inhibition of violacein production and biofilm formation by cis-cis-p-menthenolide might be related to a disruption in the QS mechanism.

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Section: Methodsmentioning

confidence: 99%

Anti-Quorum Sensing Activity of 12 Essential Oils on chromobacterium violaceum and Specific Action of cis-cis-p-Menthenolide from Corsican Mentha suaveolens ssp. Insularis

et al. 2018

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“…Moreover, these ocimene-type oils contained an appreciable amount of alismol (1.7 and 1.6%), an unusual sesquiterpene in Citrus. Indeed, occurrences of alismol in Citrus oils have already been found in kumquats (Fortunella genus) [42] and in C. × jambhiri Lush. [43].…”

Section: Section Papedocitrus Ichang Papeda (C Ichangensis Swingle)mentioning

confidence: 97%

Chemical Variability of Peel and Leaf Essential Oils in the Citrus Subgenus Papeda (Swingle) and Few Relatives

Baccati

Gibernau

Paoli

et al. 2021

Plants

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The Papeda Citrus subgenus includes several species belonging to two genetically distinct groups, containing mostly little-exploited wild forms of citrus. However, little is known about the potentially large and novel aromatic diversity contained in these wild citruses. In this study, we characterized and compared the essential oils obtained from peels and leaves from representatives of both Papeda groups, and three related hybrids. Using a combination of GC, GC-MS, and 13C-NMR spectrometry, we identified a total of 60 compounds in peel oils (PO), and 76 compounds in leaf oils (LO). Limonene was the major component in almost all citrus PO, except for C. micrantha and C. hystrix, where β-pinene dominated (around 35%). LO composition was more variable, with different major compounds among almost all samples, except for two citrus pairs: C. micrantha/C. hystrix and two accessions of C. ichangensis. In hybrid relatives, the profiles were largely consistent with their Citrus/Papeda parental lineage. This high chemical diversity, not only among the sections of the subgenus Papeda, but also between species and even at the intraspecific level, suggests that Papeda may be an important source of aroma diversity for future experimental crosses with field crop species.

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Oviposition deterrence, larvicidal activity and docking of β-germacrene-D-4-ol obtained from leaves of Piper corcovadensis (Piperaceae) against Aedes aegypti

Albuquerque

Silva

et al. 2022

Industrial Crops and Products

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Germacra‐1(10),5‐dien‐4α‐ol in Fortunella sp. leaf oils

Cited by 6 publications

References 36 publications

Anti-Quorum Sensing Activity of 12 Essential Oils on chromobacterium violaceum and Specific Action of cis-cis-p-Menthenolide from Corsican Mentha suaveolens ssp. Insularis

Anti-Quorum Sensing Activity of 12 Essential Oils on chromobacterium violaceum and Specific Action of cis-cis-p-Menthenolide from Corsican Mentha suaveolens ssp. Insularis

Chemical Variability of Peel and Leaf Essential Oils in the Citrus Subgenus Papeda (Swingle) and Few Relatives

Oviposition deterrence, larvicidal activity and docking of β-germacrene-D-4-ol obtained from leaves of Piper corcovadensis (Piperaceae) against Aedes aegypti

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