2021
DOI: 10.1101/2021.03.12.21253490
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Abstract: INTRODUCTION: Coronavirus disease (COVID-19) is a global pandemic. Vitamin D (25-OHD) deficiency has been associated with susceptibility to infectious disease. In this study, the association between COVID-19 outcomes and 25-OHD levels in patients attending a COVID-19 reference center in Mexico City are examined. METHODS: Consecutive patients with confirmed COVID-19 were evaluated. All patients underwent clinical evaluation (including outcomes), laboratory measurements (including 25-OHD) and a thoracic computer… Show more

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Cited by 4 publications
(5 citation statements)
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“…In the current study, vitamin D deficiency (<20 ng/mL) was associated with a higher risk of mortality among critically ill elderly COVID-19 patients. In line with our findings, a prospective study on 551 COVID-19 patients showed that vitamin D deficiency (≤12 ng/ml or <30 nmol/L) was significantly associated with COVID-19 mortality after controlling for visceral fat (epicardial fat thickness) 39 . In a retrospective study on 257 COVID-19 patients, Jenei et al reported that vitamin D deficiency is a potential risk factor for mortality among elderly COVID-19 patients with comorbidities (cancer, diabetes and/or pulmonary disease) 40 .…”
Section: Discussionsupporting
confidence: 91%
“…In the current study, vitamin D deficiency (<20 ng/mL) was associated with a higher risk of mortality among critically ill elderly COVID-19 patients. In line with our findings, a prospective study on 551 COVID-19 patients showed that vitamin D deficiency (≤12 ng/ml or <30 nmol/L) was significantly associated with COVID-19 mortality after controlling for visceral fat (epicardial fat thickness) 39 . In a retrospective study on 257 COVID-19 patients, Jenei et al reported that vitamin D deficiency is a potential risk factor for mortality among elderly COVID-19 patients with comorbidities (cancer, diabetes and/or pulmonary disease) 40 .…”
Section: Discussionsupporting
confidence: 91%
“…Jan, January; Fe, February; Mar, March; Apr, April; Jun, June; Jul, July; 25OHD <25, 25OHD levels <25 nmol/L; 25OHD <50, 25OHD levels <50 nmol/L; 25OHD <75, 25OHD levels <75 nmol/L. The studies by Mendy et al ( 37 ) by Vanegas-Cedillo et al ( 84 ) by Vashegani et al ( 98 ) and by Walk ( 86 ) are in preprint form .…”
Section: Resultsmentioning
confidence: 95%
“…The quality of included studies varied consistently, with a NOS between 3 and 9 (median score 6). The 25OHD levels have been determined: (i) before SARS-CoV-2 test in 5 studies ( 45 , 50 , 51 , 56 , 59 ) and at SARS-CoV-2 test in 12 studies ( 46 49 , 52 55 , 57 , 58 , 60 , 61 ), (ii) before COVID-19 diagnosis in 3 studies ( 63 , 64 , 66 ) and at COVID-19 diagnosis in 6 studies, ( 49 , 57 , 60 , 62 , 65 , 67 ), and (iii) before COVID-19 related hospitalization in 7 studies ( 63 , 64 , 66 , 74 , 80 , 83 , 93 ), and at COVID-19 related hospitalization in 35 studies ( 49 , 52 , 55 , 57 , 58 , 61 , 65 , 67 73 , 75 – 79 , 81 , 82 , 84 92 , 94 98 ).…”
Section: Resultsmentioning
confidence: 99%
“…A rapidly increasing number of publications are investigating the vitamin D3 status of SARS CoV 2 -patients and have confirmed both low vitamin D levels in cases of severe courses of infection [106][107][108][109][110][111][112][113][114][115][116][117][118][119][120][121] and positive results of vitamin D3 treatments [122][123][124][125][126][127][128]. Therefore, many scientists recommend vitamin D3 as an indispensable part of a medical treatment plan to avoid severe courses of SARS CoV 2 infection --…”
Section: (Which Was Not Certified By Peer Review) Preprintmentioning
confidence: 99%