Serum vitamin D level may be associated with body weight and body composition in male adolescents; a longitudinal study

Doaei, Saeid; Jarrahi, Seyed Alireza Mosavi; Torki, Saheb Abbas; Haghshenas, Rouhollah; Jamshidi, Zahra; Rezaei, Shahla; Moslem, Alireza; Ghorat, Fereshteh; Khodabakhshi, Adeleh

doi:10.5114/pedm.2020.97466

Cited by 13 publications

(6 citation statements)

References 44 publications

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“…Our study also found that body weight exclusively breastfed infants was positively associated with infant vitamin D su ciency. Existing studies mostly focused on vitamin D and obesity in non-children, and it is commonly recognized that serum vitamin D is lower in high body weight and obese people (30,31), but recent evidence from review a study indicated that the link between vitamin D and obesity remains controversial due to important limitations and confounding of studies (32). Current study on the infant body weight and serum vitamin D status are scare.…”

Section: Discussionmentioning

confidence: 99%

Serum vitamin D levels in lactating mothers and their exclusive breastfeeding infants with symptoms of rickets

Song

Liu

et al. 2022

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Objective To evaluate the vitamin D status in postpartum women during lactation and their exclusively breastfed infants with symptoms of rickets at 4–6 weeks after birth. Factors associated with breastfed infant serum vitamin D status were also determined. Methods One hundred and two exclusively breastfeeding infants with symptoms of nutritional rickets and their mothers were recruited in this study. Sociodemographic and clinical data including blood samples were collected during their visit to the children healthcare counseling clinic. Lactating mothers and their nursing infants were classified into sufficient, insufficient, and deficient according to serum 25(OH)D levels. Multivariate logistical regression model was used to analyses the final adjusted odds ratio and 95% CI. Results The prevalence of vitamin D sufficiency in lactating mother and exclusively breastfed infants were 8.7% and 40.2%, respectively. Final multiple logistic regression showed that infant daily vitamin D intake and body weight were statistically significantly associated with vitamin D status. Infant who had a vitamin D intake of > 400 IU per day (adjusted OR, 3.47; 95%CI, 1.06–11.30) was more likely to be vitamin D sufficiency. Infant with a higher body weight was associated with vitamin D sufficient status (adjusted OR, 2.01; 95%CI, 1.11–3.66). Conclusions Our study shows a very low prevalence of 25(OH)D sufficiency in lactating mothers, and a moderate vitamin D sufficiency in the exclusive breastfeeding infants with symptoms of rickets. Infant daily vitamin D intake and body weight were related to their vitamin D status. Findings of this study indicate the importance of vitamin D supplementation to maintain sufficient 25(OH)D levels in infants.

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Section: Discussionmentioning

confidence: 99%

Serum vitamin D levels in lactating mothers and their exclusive breastfeeding infants with symptoms of rickets

Song

Liu

et al. 2022

Preprint

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“…The reason for these differences may be the differences in doses of vitamin D supplementation and also differences in seum level of vitamin D. Doaei et al reported that the serum level of vitamin D is inversely associated with obesity. However, short term changes of serum vitamin D was not related to changes in weight ( Doaei et al, 2020 ).…”

Section: Discussionmentioning

confidence: 99%

The Effects of Vitamin D Supplementation on Anthropometric and Biochemical Indices in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis

et al. 2021

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Background: Vitamin D was reported to be associated with non−alcoholic fatty liver disease (NAFLD). This systematic review and meta−analysis aimed to investigate the effects of the vitamin D supplementation on anthropometric and biochemical indices in patient with NAFLD.Methods: PubMed, Web of science, Scopus, and Embase databases were explored to identify all randomized controlled trial (RCT) investigating the effects of vitamin D supplementation on anthropometric and biochemical indices in patients with NAFLD. A random−effects model was used to pool weighted mean difference (WMD) and corresponding 95% confidence intervals (CIs). The statistical heterogeneity among the studies was assessed using I2 statistic (high ≥ 50%, low < 50%) and Cochran’s Q−test.Results: Sixteen RCTs were included in this meta−analysis. The results identified that high−density lipoprotein−cholesterol (HDL−C) level significantly increased following vitamin D supplementation (P = 0.008). Vitamin D reduced body weight (P = 0.007), body mass index (P = 0.002), waist circumstance (WC) (P = 0.02), serum alanine transaminase (ALT) (P = 0.01), fasting blood sugar (FBS) (P = 0.01), homeostatic model assessment for insulin resistance (HOMA−IR) (P = 0.004), and calcium (P = 0.01). No significant changes were found on body fat, triglyceride (TG), total cholesterol, low−density lipoprotein−cholesterol (LDL−C), aspartate transaminase, alkaline phosphatase, gamma−glutamyl transferase, and adiponectin following vitamin D supplementation.Conclusion: Vitamin D had significant effects on anthropometric and biochemical indices including HDL−C, body weight, BMI, WC, serum ALT, serum FBS, HOMA−IR, and calcium. Vitamin D supplementation can be considered as an effective strategy in management of patients with NAFLD.Systematic Review Registration: [website], identifier [registration number]

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“…Moreover, low levels of vitamin D were also associated with an increase in adiposity and a higher fat infiltration in the muscle tissue [ 27 ]. In fact, vitamin D levels were lower among adolescents with obesity when compared with non-obese individuals [ 28 ]. It is important to note that low vitamin D levels in children have been linked to obesity but not to other cardiovascular risk factors such as hyperglycemia [ 29 ].…”

Section: Dietary Management Of Diabetes and Bone Metabolism: Do They ...mentioning

confidence: 99%

Treatment of Diabetes and Osteoporosis—A Reciprocal Risk?

et al. 2022

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Diabetes mellitus is a metabolic and systematic disorder that requires individualized therapy. The disease leads to various consequences, resulting in the destruction of tissues and organs. The aforementioned outcomes also include bone mineral disorders, caused by medications as well as diet therapy and physical activity. Some drugs may have a beneficial effect on both bone mineral density and the risk of fractures. Nevertheless, the impact of other medications remains unknown. Focusing on pharmacotherapy in diabetes may prevent bone mineral disorders and influence both the treatment and quality of life in patients suffering from diabetes mellitus. On the other hand, anti-osteoporosis drugs, such as antiresorptive or anabolic drugs, as well as drugs with a mixed mechanism of action, may affect carbohydrate metabolism, particularly in patients with diabetes. Therefore, the treatment of diabetes as well as osteoporosis prevention are vital for this group of patients.

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Serum vitamin D level may be associated with body weight and body composition in male adolescents; a longitudinal study

Cited by 13 publications

References 44 publications

Serum vitamin D levels in lactating mothers and their exclusive breastfeeding infants with symptoms of rickets

Serum vitamin D levels in lactating mothers and their exclusive breastfeeding infants with symptoms of rickets

The Effects of Vitamin D Supplementation on Anthropometric and Biochemical Indices in Patients With Non-alcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis

Treatment of Diabetes and Osteoporosis—A Reciprocal Risk?

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