1997
DOI: 10.1177/000456329703400113
|View full text |Cite
|
Sign up to set email alerts
|

Serum Total Antioxidant Activity after Myocardial Infarction

Abstract: Serum total antioxidant activity (TAA), albumin and uric acid were measured on admission, and for the next 2 days in 56 patients suffering myocardial infarction, 20 of whom received streptokinase. The ‘antioxidant gap’, the difference between the serum TAA and the sum of the serum albumin and uric acid activity, was calculated. No significant changes in serum total antioxidant activity were observed in either group of patients between admission, day 1 and day 2. However, a decline in the ‘antioxidant gap’ afte… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

5
30
0

Year Published

1998
1998
2015
2015

Publication Types

Select...
9
1

Relationship

0
10

Authors

Journals

citations
Cited by 40 publications
(35 citation statements)
references
References 32 publications
5
30
0
Order By: Relevance
“…Ann Clin Biochem 1998; 35 Total plasma antioxidant status During CPB, the absolute concentration of TPAS showed a significant decrease (P=0'0002) 1·5h postoperatively which was sustained for 24 h, with a gradual increase towards preoperative values (see Table I, Fig. I).…”
Section: Resultsmentioning
confidence: 95%
“…Ann Clin Biochem 1998; 35 Total plasma antioxidant status During CPB, the absolute concentration of TPAS showed a significant decrease (P=0'0002) 1·5h postoperatively which was sustained for 24 h, with a gradual increase towards preoperative values (see Table I, Fig. I).…”
Section: Resultsmentioning
confidence: 95%
“…Plasma UA was measured enzymatically using a uricase/peroxidase-based reaction on the Roche Modular system (Roche Diagnostics, Lewes, UK). The AO gap (AOG) was calculated as described by Miller et al 20 by subtracting values derived from plasma concentrations of UA and albumin from TAS; that test was used for correlation testing, a two-sided P value of o0.05 being taken as signi¢cant.…”
Section: Methodsmentioning
confidence: 99%
“…20 The change in absorbance was measured at 460 nm (" 11 300/mol per cm) for 5 min. Results were expressed as units of MPO/ mg protein, with 1 unit of MPO defined as the quantity of enzyme degrading 1 nmol hydrogen peroxide/min at 25 C. Total antioxidant activity was determined using the 6-hydroxy-2,5,7,8-tetramethylchroman-2 carboxylic acid (Trolox) equivalent antioxidant capacity (TEAC) assay developed by Miller et al, 21 with modifications. 22 Optical density (absorbance) was read at 734 nm against 5 mmol/l phosphate-buffered saline (pH 7.4).…”
Section: Sample Analysismentioning
confidence: 99%